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L1cam-mediated developmental processes of the nervous system are differentially regulated by proteolytic processing
Normal brain development depends on tight temporal and spatial regulation of connections between cells. Mutations in L1cam, a member of the immunoglobulin (Ig) superfamily that mediate cell-cell contacts through homo- and heterophilic interactions, are associated with several developmental abnormali...
Autores principales: | Linneberg, Cecilie, Toft, Christian Liebst Frisk, Kjaer-Sorensen, Kasper, Laursen, Lisbeth S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403279/ https://www.ncbi.nlm.nih.gov/pubmed/30842511 http://dx.doi.org/10.1038/s41598-019-39884-x |
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