Bacillus Calmette-Guérin Induces PD-L1 Expression on Antigen-Presenting Cells via Autocrine and Paracrine Interleukin-STAT3 Circuits

Bacillus Calmette-Guérin (BCG) is the only licensed vaccine for tuberculosis (TB), and is also used as an immunotherapy for bladder cancer and other malignancies due to its immunostimulatory properties. Mycobacteria spp., however, are well known for their numerous immune evasion mechanisms that limi...

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Detalles Bibliográficos
Autores principales: Copland, Alastair, Sparrow, Adam, Hart, Peter, Diogo, Gil Reynolds, Paul, Mathew, Azuma, Miyuki, Reljic, Rajko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403281/
https://www.ncbi.nlm.nih.gov/pubmed/30842561
http://dx.doi.org/10.1038/s41598-019-40145-0

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