Cargando…

Development of selective cytotoxic viral vectors for concentration of undifferentiated cells in cardiomyocytes derived from human induced pluripotent stem cells

Cell-processed therapeutic products (CTPs) derived from human pluripotent stem cells (hPSCs) have innovative applications in regenerative medicine. However, undifferentiated hPSCs possess tumorigenic potential; thus, sensitive methods for the detection of residual undifferentiated hPSCs are essentia...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kono, Ken, Sawada, Rumi, Kuroda, Takuya, Yasuda, Satoshi, Matsuyama, Satoko, Matsuyama, Akifumi, Mizuguchi, Hiroyuki, Sato, Yoji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403330/ https://www.ncbi.nlm.nih.gov/pubmed/30842516 http://dx.doi.org/10.1038/s41598-018-36848-5

Ejemplares similares

A selective cytotoxic adenovirus vector for concentration of pluripotent stem cells in human pluripotent stem cell-derived neural progenitor cells
por: Hirai, Takamasa, et al.
Publicado: (2021)

Highly sensitive droplet digital PCR method for detection of residual undifferentiated cells in cardiomyocytes derived from human pluripotent stem cells
por: Kuroda, Takuya, et al.
Publicado: (2015)

SALL3 expression balance underlies lineage biases in human induced pluripotent stem cell differentiation
por: Kuroda, Takuya, et al.
Publicado: (2019)

Application of cell growth analysis to the quality assessment of human cell-processed therapeutic products as a testing method for immortalized cellular impurities
por: Hasebe-Takada, Nozomi, et al.
Publicado: (2016)

Identification of a Gene Encoding Slow Skeletal Muscle Troponin T as a Novel Marker for Immortalization of Retinal Pigment Epithelial Cells
por: Kuroda, Takuya, et al.
Publicado: (2017)

A Novel In Vitro Method for Detecting Undifferentiated Human Pluripotent Stem Cells as Impurities in Cell Therapy Products Using a Highly Efficient Culture System
por: Tano, Keiko, et al.
Publicado: (2014)

Tumorigenicity-associated characteristics of human iPS cell lines
por: Yasuda, Satoshi, et al.
Publicado: (2018)

Single-Cell RNA-Seq Reveals LRRC75A-Expressing Cell Population Involved in VEGF Secretion of Multipotent Mesenchymal Stromal/Stem Cells Under Ischemia
por: Miura, Takumi, et al.
Publicado: (2023)

Induced Pluripotent Stem Cells: Global Research Trends
por: Negoro, Takaharu, et al.
Publicado: (2017)

Cytotoxicity of propofol in human induced pluripotent stem cell-derived cardiomyocytes
por: Kido, Koji, et al.
Publicado: (2017)

Patent Application Trends of Induced Pluripotent Stem Cell Technologies in the United States, Japanese, and European Applications
por: Morita, Yasushi, et al.
Publicado: (2019)

Salicylic diamines selectively eliminate residual undifferentiated cells from pluripotent stem cell-derived cardiomyocyte preparations
por: Burkert, Karsten, et al.
Publicado: (2021)

Prediction of Differentiation Tendency Toward Hepatocytes from Gene Expression in Undifferentiated Human Pluripotent Stem Cells
por: Yanagihara, Kana, et al.
Publicado: (2016)

Highly Sensitive In Vitro Methods for Detection of Residual Undifferentiated Cells in Retinal Pigment Epithelial Cells Derived from Human iPS Cells
por: Kuroda, Takuya, et al.
Publicado: (2012)

A study on ensuring the quality and safety of pharmaceuticals and medical devices derived from processing of autologous human induced pluripotent stem(-like) cells()
por: Hayakawa, Takao, et al.
Publicado: (2015)

A study on ensuring the quality and safety of pharmaceuticals and medical devices derived from processing of allogeneic human induced pluripotent stem(-Like) cells()
por: Hayakawa, Takao, et al.
Publicado: (2015)

In Vitro Endothelialization Test of Biomaterials Using Immortalized Endothelial Cells
por: Kono, Ken, et al.
Publicado: (2016)

Characterization of in vivo tumorigenicity tests using severe immunodeficient NOD/Shi-scid IL2Rγ(null) mice for detection of tumorigenic cellular impurities in human cell-processed therapeutic products
por: Kusakawa, Shinji, et al.
Publicado: (2015)

Undifferentiated carcinoma of the liver: a case report with immunohistochemical analysis
por: Maeda, Takashi, et al.
Publicado: (2017)

Plasma-activated medium selectively eliminates undifferentiated human induced pluripotent stem cells
por: Matsumoto, Ryo, et al.
Publicado: (2016)

Conditionally replicating adenovirus prevents pluripotent stem cell–derived teratoma by specifically eliminating undifferentiated cells
por: Mitsui, Kaoru, et al.
Publicado: (2015)

Endothelin‐1 Induces Myofibrillar Disarray and Contractile Vector Variability in Hypertrophic Cardiomyopathy–Induced Pluripotent Stem Cell–Derived Cardiomyocytes
por: Tanaka, Atsushi, et al.
Publicado: (2014)

Vinblastine treatment decreases the undifferentiated cell contamination of human iPSC-derived intestinal epithelial-like cells
por: Ichikawa, Moe, et al.
Publicado: (2021)

Non-viral vector based gene transfection with human induced pluripotent stem cells derived cardiomyocytes
por: Tan, Shihua, et al.
Publicado: (2019)

Expression of Chrna9 is regulated by Tbx3 in undifferentiated pluripotent stem cells
por: Yazawa, Takashi, et al.
Publicado: (2023)

Sialyl-lactotetra, a Novel Cell Surface Marker of Undifferentiated Human Pluripotent Stem Cells
por: Barone, Angela, et al.
Publicado: (2014)

Method for selective ablation of undifferentiated human pluripotent stem cell populations for cell-based therapies
por: Chour, Tony, et al.
Publicado: (2021)

Intramyocardial Transplantation of Undifferentiated Rat Induced Pluripotent Stem Cells Causes Tumorigenesis in the Heart
por: Zhang, Yuzhen, et al.
Publicado: (2011)

MicroRNA-302 switch to identify and eliminate undifferentiated human pluripotent stem cells
por: Parr, Callum J. C., et al.
Publicado: (2016)

Evaluation of the reproducibility and positive controls of cellular immortality test for the detection of immortalized cellular impurities in human cell-processed therapeutic products
por: Hirai, Takamasa, et al.
Publicado: (2022)

Co-culture of induced pluripotent stem cells with cardiomyocytes is sufficient to promote their differentiation into cardiomyocytes
por: Chu, Axel J., et al.
Publicado: (2020)

Trends in clinical trials for articular cartilage repair by cell therapy
por: Negoro, Takaharu, et al.
Publicado: (2018)

The pluripotency factor LIN28 marks undifferentiated spermatogonia in mouse
por: Zheng, Ke, et al.
Publicado: (2009)

Imaging-cytometry revealed spatial heterogeneities of marker expression in undifferentiated human pluripotent stem cells
por: Suga, Mika, et al.
Publicado: (2016)

Undifferentiated Induced Pluripotent Stem Cells as a Genetic Model for Nonalcoholic Fatty Liver Disease
por: Muñoz, Antonio, et al.
Publicado: (2022)

Assessment of the In Vitro Cytotoxicity Effects of the Leaf Methanol Extract of Crinum zeylanicum on Mouse Induced Pluripotent Stem Cells and Their Cardiomyocytes Derivatives
por: Ndjenda II, Magloire Kanyou, et al.
Publicado: (2021)

Uses of cardiomyocytes generated from induced pluripotent stem cells
por: Lu, Tung-Ying, et al.
Publicado: (2011)

Atomic Force Mechanobiology of Pluripotent Stem Cell-Derived Cardiomyocytes
por: Liu, Jianwei, et al.
Publicado: (2012)

Directed Differentiation of Zebrafish Pluripotent Embryonic Cells to Functional Cardiomyocytes
por: Xiao, Yao, et al.
Publicado: (2016)

Maturation of pluripotent stem cell derived cardiomyocytes: The new challenge
por: Aigha, Idil, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_8nrrtnvp6poqovf785p5bnth40