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Accumulation of genetic and epigenetic alterations in normal cells and cancer risk
Cancers develop due to the accumulation of genetic and epigenetic alterations. Genetic alterations are induced by aging, mutagenic chemicals, ultraviolet light, and other factors; whereas, epigenetic alterations are mainly by aging and chronic inflammation. The accumulation and patterns of alteratio...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403339/ https://www.ncbi.nlm.nih.gov/pubmed/30854468 http://dx.doi.org/10.1038/s41698-019-0079-0 |