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Notch Signaling Mediates Astrocyte Abnormality in Spinal Muscular Atrophy Model Systems

Spinal muscular atrophy (SMA) is an autosomal recessive neuromuscular disorder characterized by the degeneration of spinal motor neurons and muscle atrophy. The disease is mainly caused by low level of the survival motor neuron (SMN) protein, which is coded by two genes, namely SMN1 and SMN2, but le...

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Detalles Bibliográficos
Autores principales:	Ohuchi, Kazuki, Funato, Michinori, Yoshino, Yuta, Ando, Shiori, Inagaki, Satoshi, Sato, Arisu, Kawase, Chizuru, Seki, Junko, Saito, Toshio, Nishio, Hisahide, Nakamura, Shinsuke, Shimazawa, Masamitsu, Kaneko, Hideo, Hara, Hideaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403369/ https://www.ncbi.nlm.nih.gov/pubmed/30842449 http://dx.doi.org/10.1038/s41598-019-39788-w

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