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Genetic dissection of Nodal and Bmp signalling requirements during primordial germ cell development in mouse
The essential roles played by Nodal and Bmp signalling during early mouse development have been extensively documented. Here we use conditional deletion strategies to investigate functional contributions made by Nodal, Bmp and Smad downstream effectors during primordial germ cell (PGC) development....
Autores principales: | Senft, Anna D., Bikoff, Elizabeth K., Robertson, Elizabeth J., Costello, Ita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403387/ https://www.ncbi.nlm.nih.gov/pubmed/30842446 http://dx.doi.org/10.1038/s41467-019-09052-w |
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