Collagen type II suppresses articular chondrocyte hypertrophy and osteoarthritis progression by promoting integrin β1−SMAD1 interaction

Hypertrophic differentiation is not only the terminal process of endochondral ossification in the growth plate but is also an important pathological change in osteoarthritic cartilage. Collagen type II (COL2A1) was previously considered to be only a structural component of the cartilage matrix, but...

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Detalles Bibliográficos
Autores principales: Lian, Chengjie, Wang, Xudong, Qiu, Xianjian, Wu, Zizhao, Gao, Bo, Liu, Lei, Liang, Guoyan, Zhou, Hang, Yang, Xiaoming, Peng, Yan, Liang, Anjing, Xu, Caixia, Huang, Dongsheng, Su, Peiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403405/
https://www.ncbi.nlm.nih.gov/pubmed/30854241
http://dx.doi.org/10.1038/s41413-019-0046-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403405/
https://www.ncbi.nlm.nih.gov/pubmed/30854241
http://dx.doi.org/10.1038/s41413-019-0046-y

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