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A decade of catheter ablation of cardiac arrhythmias in Sweden: ablation practices and outcomes

AIMS: Catheter ablation is considered the treatment of choice for many tachyarrhythmias, but convincing ‘real-world’ data on efficacy and safety are lacking. Using Swedish national registry data, the ablation spectrum, procedural characteristics, as well as ablation efficacy and reported adverse eve...

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Autores principales: Holmqvist, Fredrik, Kesek, Milos, Englund, Anders, Blomström-Lundqvist, Carina, Karlsson, Lars O, Kennebäck, Göran, Poçi, Dritan, Samo-Ayou, Romeo, Sigurjónsdóttir, Runa, Ringborn, Michael, Herczku, Csaba, Carlson, Jonas, Fengsrud, Espen, Tabrizi, Fariborz, Höglund, Niklas, Lönnerholm, Stefan, Kongstad, Ole, Jönsson, Anders, Insulander, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403459/
https://www.ncbi.nlm.nih.gov/pubmed/30452631
http://dx.doi.org/10.1093/eurheartj/ehy709
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author Holmqvist, Fredrik
Kesek, Milos
Englund, Anders
Blomström-Lundqvist, Carina
Karlsson, Lars O
Kennebäck, Göran
Poçi, Dritan
Samo-Ayou, Romeo
Sigurjónsdóttir, Runa
Ringborn, Michael
Herczku, Csaba
Carlson, Jonas
Fengsrud, Espen
Tabrizi, Fariborz
Höglund, Niklas
Lönnerholm, Stefan
Kongstad, Ole
Jönsson, Anders
Insulander, Per
author_facet Holmqvist, Fredrik
Kesek, Milos
Englund, Anders
Blomström-Lundqvist, Carina
Karlsson, Lars O
Kennebäck, Göran
Poçi, Dritan
Samo-Ayou, Romeo
Sigurjónsdóttir, Runa
Ringborn, Michael
Herczku, Csaba
Carlson, Jonas
Fengsrud, Espen
Tabrizi, Fariborz
Höglund, Niklas
Lönnerholm, Stefan
Kongstad, Ole
Jönsson, Anders
Insulander, Per
author_sort Holmqvist, Fredrik
collection PubMed
description AIMS: Catheter ablation is considered the treatment of choice for many tachyarrhythmias, but convincing ‘real-world’ data on efficacy and safety are lacking. Using Swedish national registry data, the ablation spectrum, procedural characteristics, as well as ablation efficacy and reported adverse events are reported. METHODS AND RESULTS: Consecutive patients (≥18 years of age) undergoing catheter ablation in Sweden between 01 January 2006 and 31 December 2015 were included in the study. Follow-up (repeat ablation and vital status) was collected through 31 December 2016. A total of 26 642 patients (57 ± 15 years, 62% men), undergoing a total of 34 428 ablation procedures were included in the study. In total, 4034 accessory pathway/Wolff–Parkinson–White syndrome (12%), 7358 AV-nodal re-entrant tachycardia (21%), 1813 atrial tachycardia (5.2%), 5481 typical atrial flutter (16%), 11 916 atrial fibrillation (AF, 35%), 2415 AV-nodal (7.0%), 581 premature ventricular contraction (PVC, 1.7%), and 964 ventricular tachycardia (VT) ablations (2.8%) were performed. Median follow-up time was 4.7 years (interquartile range 2.7–7.0). The spectrum of treated arrhythmias changed over time, with a gradual increase in AF, VT, and PVC ablation (P < 0.001). Decreasing procedural times and utilization of fluoroscopy with time, were seen for all arrhythmia types. The rates of repeat ablation differed between ablation types, with the highest repeat ablation seen in AF (41% within 3 years). The rate of reported adverse events was low (n = 595, 1.7%). Death in the immediate period following ablation was rare (n = 116, 0.34%). CONCLUSION: Catheter ablations have shifted towards more complex procedures over the past decade. Fluoroscopy time has markedly decreased and the efficacy of catheter ablation seems to improve for AF.
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spelling pubmed-64034592019-03-12 A decade of catheter ablation of cardiac arrhythmias in Sweden: ablation practices and outcomes Holmqvist, Fredrik Kesek, Milos Englund, Anders Blomström-Lundqvist, Carina Karlsson, Lars O Kennebäck, Göran Poçi, Dritan Samo-Ayou, Romeo Sigurjónsdóttir, Runa Ringborn, Michael Herczku, Csaba Carlson, Jonas Fengsrud, Espen Tabrizi, Fariborz Höglund, Niklas Lönnerholm, Stefan Kongstad, Ole Jönsson, Anders Insulander, Per Eur Heart J Clinical Research AIMS: Catheter ablation is considered the treatment of choice for many tachyarrhythmias, but convincing ‘real-world’ data on efficacy and safety are lacking. Using Swedish national registry data, the ablation spectrum, procedural characteristics, as well as ablation efficacy and reported adverse events are reported. METHODS AND RESULTS: Consecutive patients (≥18 years of age) undergoing catheter ablation in Sweden between 01 January 2006 and 31 December 2015 were included in the study. Follow-up (repeat ablation and vital status) was collected through 31 December 2016. A total of 26 642 patients (57 ± 15 years, 62% men), undergoing a total of 34 428 ablation procedures were included in the study. In total, 4034 accessory pathway/Wolff–Parkinson–White syndrome (12%), 7358 AV-nodal re-entrant tachycardia (21%), 1813 atrial tachycardia (5.2%), 5481 typical atrial flutter (16%), 11 916 atrial fibrillation (AF, 35%), 2415 AV-nodal (7.0%), 581 premature ventricular contraction (PVC, 1.7%), and 964 ventricular tachycardia (VT) ablations (2.8%) were performed. Median follow-up time was 4.7 years (interquartile range 2.7–7.0). The spectrum of treated arrhythmias changed over time, with a gradual increase in AF, VT, and PVC ablation (P < 0.001). Decreasing procedural times and utilization of fluoroscopy with time, were seen for all arrhythmia types. The rates of repeat ablation differed between ablation types, with the highest repeat ablation seen in AF (41% within 3 years). The rate of reported adverse events was low (n = 595, 1.7%). Death in the immediate period following ablation was rare (n = 116, 0.34%). CONCLUSION: Catheter ablations have shifted towards more complex procedures over the past decade. Fluoroscopy time has markedly decreased and the efficacy of catheter ablation seems to improve for AF. Oxford University Press 2019-03-07 2018-11-17 /pmc/articles/PMC6403459/ /pubmed/30452631 http://dx.doi.org/10.1093/eurheartj/ehy709 Text en © The Author(s) 2018. Published by Oxford University Press on behalf of the European Society of Cardiology. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Clinical Research
Holmqvist, Fredrik
Kesek, Milos
Englund, Anders
Blomström-Lundqvist, Carina
Karlsson, Lars O
Kennebäck, Göran
Poçi, Dritan
Samo-Ayou, Romeo
Sigurjónsdóttir, Runa
Ringborn, Michael
Herczku, Csaba
Carlson, Jonas
Fengsrud, Espen
Tabrizi, Fariborz
Höglund, Niklas
Lönnerholm, Stefan
Kongstad, Ole
Jönsson, Anders
Insulander, Per
A decade of catheter ablation of cardiac arrhythmias in Sweden: ablation practices and outcomes
title A decade of catheter ablation of cardiac arrhythmias in Sweden: ablation practices and outcomes
title_full A decade of catheter ablation of cardiac arrhythmias in Sweden: ablation practices and outcomes
title_fullStr A decade of catheter ablation of cardiac arrhythmias in Sweden: ablation practices and outcomes
title_full_unstemmed A decade of catheter ablation of cardiac arrhythmias in Sweden: ablation practices and outcomes
title_short A decade of catheter ablation of cardiac arrhythmias in Sweden: ablation practices and outcomes
title_sort decade of catheter ablation of cardiac arrhythmias in sweden: ablation practices and outcomes
topic Clinical Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403459/
https://www.ncbi.nlm.nih.gov/pubmed/30452631
http://dx.doi.org/10.1093/eurheartj/ehy709
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