Measurement of the refractive index of whole blood and its components for a continuous spectral region

The refractive index of blood is a key biophysical parameter, which can reflect the physiological state. We measured the refractive index of whole blood and other components, such as serum, plasma, and hemoglobin, based on internal reflection by using a homemade apparatus in the spectral range of 40...

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Autores principales: Liu, Shike, Deng, Zhichao, Li, Jianwei, Wang, Jin, Huang, Ningning, Cui, Ruiming, Zhang, Qiannan, Mei, Jianchun, Zhou, Wenyuan, Zhang, Chunping, Ye, Qing, Tian, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Photo-Optical Instrumentation Engineers 2019
Materias:
General
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403469/
https://www.ncbi.nlm.nih.gov/pubmed/30848110
http://dx.doi.org/10.1117/1.JBO.24.3.035003
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author Liu, Shike
Deng, Zhichao
Li, Jianwei
Wang, Jin
Huang, Ningning
Cui, Ruiming
Zhang, Qiannan
Mei, Jianchun
Zhou, Wenyuan
Zhang, Chunping
Ye, Qing
Tian, Jianguo
author_facet Liu, Shike
Deng, Zhichao
Li, Jianwei
Wang, Jin
Huang, Ningning
Cui, Ruiming
Zhang, Qiannan
Mei, Jianchun
Zhou, Wenyuan
Zhang, Chunping
Ye, Qing
Tian, Jianguo
author_sort Liu, Shike
collection PubMed
description The refractive index of blood is a key biophysical parameter, which can reflect the physiological state. We measured the refractive index of whole blood and other components, such as serum, plasma, and hemoglobin, based on internal reflection by using a homemade apparatus in the spectral range of 400 to 750 nm. In addition to the hemoglobin solution, which has a Soret band about 420 nm and two Q-bands between 500 and 600 nm, the measurements of other samples are the normal dispersion curve. The results are approximated by the Cauchy equation and Sellmeier equation, and the correlation coefficients are more than 0.997.
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spelling pubmed-64034692020-01-22 Measurement of the refractive index of whole blood and its components for a continuous spectral region Liu, Shike Deng, Zhichao Li, Jianwei Wang, Jin Huang, Ningning Cui, Ruiming Zhang, Qiannan Mei, Jianchun Zhou, Wenyuan Zhang, Chunping Ye, Qing Tian, Jianguo J Biomed Opt General The refractive index of blood is a key biophysical parameter, which can reflect the physiological state. We measured the refractive index of whole blood and other components, such as serum, plasma, and hemoglobin, based on internal reflection by using a homemade apparatus in the spectral range of 400 to 750 nm. In addition to the hemoglobin solution, which has a Soret band about 420 nm and two Q-bands between 500 and 600 nm, the measurements of other samples are the normal dispersion curve. The results are approximated by the Cauchy equation and Sellmeier equation, and the correlation coefficients are more than 0.997. Society of Photo-Optical Instrumentation Engineers 2019-03-07 2019-03 /pmc/articles/PMC6403469/ /pubmed/30848110 http://dx.doi.org/10.1117/1.JBO.24.3.035003 Text en © The Authors. Published by SPIE under a Creative Commons Attribution 4.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.
spellingShingle General
Liu, Shike
Deng, Zhichao
Li, Jianwei
Wang, Jin
Huang, Ningning
Cui, Ruiming
Zhang, Qiannan
Mei, Jianchun
Zhou, Wenyuan
Zhang, Chunping
Ye, Qing
Tian, Jianguo
Measurement of the refractive index of whole blood and its components for a continuous spectral region
title Measurement of the refractive index of whole blood and its components for a continuous spectral region
title_full Measurement of the refractive index of whole blood and its components for a continuous spectral region
title_fullStr Measurement of the refractive index of whole blood and its components for a continuous spectral region
title_full_unstemmed Measurement of the refractive index of whole blood and its components for a continuous spectral region
title_short Measurement of the refractive index of whole blood and its components for a continuous spectral region
title_sort measurement of the refractive index of whole blood and its components for a continuous spectral region
topic General
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403469/
https://www.ncbi.nlm.nih.gov/pubmed/30848110
http://dx.doi.org/10.1117/1.JBO.24.3.035003
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