Inhibition of the PI3K/AKT signaling pathway sensitizes diffuse large B-cell lymphoma cells to treatment with proteasome inhibitors via suppression of BAG3

Proteasome inhibitors represent a novel class of drugs that have clinical efficacy against hematological and solid cancer types, including acute myeloid leukaemia, myelodysplastic syndrome an non-small cell lung cancer. It has been demonstrated that the anti-apoptotic protein B-cell lymphoma-2-assoc...

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Detalles Bibliográficos
Autores principales: Yuan, Ting, Zhang, Feng, Zhou, Xiangxiang, Li, Ying, Zhang, Ya, Xu, Yangyang, Wang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403502/
https://www.ncbi.nlm.nih.gov/pubmed/30881494
http://dx.doi.org/10.3892/ol.2019.10029

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