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Sustained Delivery of Analgesic and Antimicrobial Agents to Knee Joint by Direct Injections of Electrosprayed Multipharmaceutical-Loaded Nano/Microparticles
In this study, we developed biodegradable lidocaine–/vancomycin–/ceftazidime–eluting poly(d,l–lactide–co–glycolide) (PLGA) nano/microparticulate carriers using an electrospraying process, and we evaluated the release behaviors of the carriers in knee joints. To prepare the particles, predetermined w...
Autores principales: | Hsu, Yung-Heng, Chen, Dave Wei-Chih, Li, Min-Jhan, Yu, Yi-Hsun, Chou, Ying-Chao, Liu, Shih-Jung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403761/ https://www.ncbi.nlm.nih.gov/pubmed/30960815 http://dx.doi.org/10.3390/polym10080890 |
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