Cargando…

PBN11-8, a Cytotoxic Polypeptide Purified from Marine Bacillus, Suppresses Invasion and Migration of Human Hepatocellular Carcinoma Cells by Targeting Focal Adhesion Kinase Pathways

The development of antitumor drugs has attracted cancer researchers and the identification of novel antitumor lead compounds is certainly of great interest. The fermentation broth of Bacillus sp. N11-8, which was isolated from the Antarctic waters, showed cytotoxicity towards different cells. A cyto...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zheng, Lanhong, Zhu, Xiangjie, Yang, Kangli, Zhu, Meihong, Farooqi, Ammad Ahmad, Kang, Daole, Sun, Mi, Xu, Yixin, Lin, Xiukun, Feng, Yingang, Liang, Fangfang, Zhang, Fuming, Linhardt, Robert J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403900/ https://www.ncbi.nlm.nih.gov/pubmed/30960968 http://dx.doi.org/10.3390/polym10091043

Ejemplares similares

Correction: Zheng, L., et al. PBN11-8, a Cytotoxic Polypeptide Purified from Marine Bacillus, Suppresses Invasion and Migration of Human Hepatocellular Carcinoma Cells by Targeting Focal Adhesion Kinase Pathways. Polymers 2018, 10, 1043
por: Zheng, Lanhong, et al.
Publicado: (2021)

Screening of microorganisms from Antarctic surface water and cytotoxicity metabolites from Antarctic microorganisms
por: Zheng, Lanhong, et al.
Publicado: (2015)

PBN-PVT projections modulate negative affective states in mice
por: Zhu, Ya-Bing, et al.
Publicado: (2022)

Neuroprotection by S-PBN in hyperglycemic ischemic brain injury in rats
por: Molnar, Maria, et al.
Publicado: (2010)

optPBN: An Optimisation Toolbox for Probabilistic Boolean Networks
por: Trairatphisan, Panuwat, et al.
Publicado: (2014)

Recent progress in fungus-derived bioactive agents for targeting of signaling machinery in cancer cells
por: Lin, Xiukun, et al.
Publicado: (2015)

Correction: optPBN: An Optimisation Toolbox for Probabilistic Boolean Networks
Publicado: (2014)

Isolation and Characterization of Marine Brevibacillus sp. S-1 Collected from South China Sea and a Novel Antitumor Peptide Produced by the Strain
por: Zheng, Lanhong, et al.
Publicado: (2014)

Genetically and functionally defined NTS to PBN brain circuits mediating anorexia
por: Roman, Carolyn W., et al.
Publicado: (2016)

Divergent changes in PBN excitability in a mouse model of neuropathic pain
por: Torruella-Suárez, María L, et al.
Publicado: (2023)

CS5931, a Novel Polypeptide in Ciona savignyi, Represses Angiogenesis via Inhibiting Vascular Endothelial Growth Factor (VEGF) and Matrix Metalloproteinases (MMPs)
por: Liu, Ge, et al.
Publicado: (2014)

Impact of Bariatric Surgical Intervention on Peripheral Blood Neutrophil (PBN) Function in Obesity
por: Roberts, Helen M., et al.
Publicado: (2017)

Large Negative Poisson’s Ratio and Anisotropic Mechanics in New Penta-PBN Monolayer
por: Sharma, Shambhu Bhandari, et al.
Publicado: (2022)

Leptin-inhibited PBN neurons enhance counter-regulatory responses to hypoglycemia in negative energy balance
por: Flak, Jonathan N., et al.
Publicado: (2014)

The Leishmania donovani Ortholog of the Glycosylphosphatidylinositol Anchor Biosynthesis Cofactor PBN1 Is Essential for Host Infection
por: Roberts, Adam, et al.
Publicado: (2022)

Veratridine modification of the purified sodium channel alpha- polypeptide from eel electroplax
Publicado: (1989)

mRNA translation and protein synthesis: an analysis of different modelling methodologies and a new PBN based approach
por: Zhao, Yun-Bo, et al.
Publicado: (2014)

Investigation of Using Sky Openness Ratio as Predictor for Navigation Performance in Urban-like Environment to Support PBN in UTM
por: Deng, Chao, et al.
Publicado: (2022)

Identification of TbPBN1 in Trypanosoma brucei reveals a conserved heterodimeric architecture for glycosylphosphatidylinositol‐mannosyltransferase‐I
por: Cowton, Andrew, et al.
Publicado: (2021)

Aplysin Sensitizes Cancer Cells to TRAIL by Suppressing P38 MAPK/Survivin Pathway
por: Liu, Jia, et al.
Publicado: (2014)

Zinc-Doped Copper Oxide Nanocomposites Inhibit the Growth of Pancreatic Cancer by Inducing Autophagy Through AMPK/mTOR Pathway
por: Li, Xiao, et al.
Publicado: (2019)

Selective optogenetic modulation of the PBN terminals in the lateral hypothalamic area and basal forebrain regulates emergence from isoflurane anesthesia in mice
por: Lu, Kai, et al.
Publicado: (2023)

Interactions of marine sulfated glycans with antithrombin and platelet factor 4
por: Zhang, Wenjing, et al.
Publicado: (2022)

Purified plasma membranes inhibit polypeptide growth factor-induced DNA synthesis in subconfluent 3T3 cells
Publicado: (1984)

PBN (Phenyl-N-Tert-Butylnitrone)-Derivatives Are Effective in Slowing the Visual Cycle and Rhodopsin Regeneration and in Protecting the Retina from Light-Induced Damage
por: Stiles, Megan, et al.
Publicado: (2015)

Addition of Popular Exogenous Antioxidant Agent, PBN, to Culture Media May Be an Important Step to Optimization of Myogenic Stem/Progenitor Cell Preparation Protocol
por: Nowaczyk, Magdalena, et al.
Publicado: (2021)

Granulin A Synergizes with Cisplatin to Inhibit the Growth of Human Hepatocellular Carcinoma
por: Qiao, Gan, et al.
Publicado: (2018)

FOCAL OR INSULAR NECROSIS PRODUCED BY THE BACILLUS OF TUBERCULOSIS
por: Le Count, E. R.
Publicado: (1897)

Reactive Oxygen Species and Autophagy Modulation in Non-Marine Drugs and Marine Drugs
por: Farooqi, Ammad Ahmad, et al.
Publicado: (2014)

Special Issue on Cancer Smart Nanomedicine
por: Pinheiro, Marina, et al.
Publicado: (2023)

Implications of Glycosaminoglycans on Viral Zoonotic Diseases
por: Bauer, Sarah, et al.
Publicado: (2021)

Pair formation and promiscuity of cytokeratins: formation in vitro of heterotypic complexes and intermediate-sized filaments by homologous and heterologous recombinations of purified polypeptides
Publicado: (1985)

Membrane-Based Inverse Transition Cycling: An Improved Means for Purifying Plant-Derived Recombinant Protein-Elastin-Like Polypeptide Fusions
por: Phan, Hoang Trong, et al.
Publicado: (2011)

Amphiphilic mPEG-Modified Oligo-Phenylalanine Nanoparticles Chemoenzymatically Synthesized via Papain
por: Wang, Feng, et al.
Publicado: (2020)

Preparation and Antitumor Activity of CS5931, A Novel Polypeptide from Sea Squirt Ciona Savignyi
por: Chen, Xiaoshuang, et al.
Publicado: (2016)

Overview on the complexity of androgen receptor-targeted therapy for prostate cancer
por: Farooqi, Ammad Ahmad, et al.
Publicado: (2015)

SPR Biosensor Probing the Interactions between TIMP-3 and Heparin/GAGs
por: Zhang, Fuming, et al.
Publicado: (2015)

Evaluation of cross-linked aggregates from purified Bacillus subtilis levansucrase mutants for transfructosylation reactions
por: Ortiz-Soto, Maria Elena, et al.
Publicado: (2009)

Algae extracts and methyl jasmonate anti-cancer activities in prostate cancer: choreographers of ‘the dance macabre’
por: Farooqi, Ammad Ahmad, et al.
Publicado: (2012)

TRAIL and vitamins: opting for keys to castle of cancer proteome instead of open sesame
por: Farooqi, Ammad Ahmad, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_v591fjomtbh7fncr4gu4fkqot0