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Near-Infrared-Responsive Cancer Photothermal and Photodynamic Therapy Using Gold Nanoparticles
Rapid growth of nanotechnology is one of the most quickly emerging tendencies in cancer therapy. Gold nanoparticles roused a distinctive interest in the field, due to their incomparable light-to-thermal energy conversion efficiency, and their ability to load and deliver a variety of anticancer drugs...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403910/ https://www.ncbi.nlm.nih.gov/pubmed/30960886 http://dx.doi.org/10.3390/polym10090961 |
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author | Kim, Hyung Shik Lee, Dong Yun |
author_facet | Kim, Hyung Shik Lee, Dong Yun |
author_sort | Kim, Hyung Shik |
collection | PubMed |
description | Rapid growth of nanotechnology is one of the most quickly emerging tendencies in cancer therapy. Gold nanoparticles roused a distinctive interest in the field, due to their incomparable light-to-thermal energy conversion efficiency, and their ability to load and deliver a variety of anticancer drugs. Therefore, simultaneous photothermal (PTT) and photodynamic (PDT) cancer therapy is available by the role of the thermal agent of the gold nanoparticle itself and the drug delivery carrier for photosensitizer (PS) transport. In this review, the physical, chemical, and biological properties of gold nanoparticle, which can promote PTT and PDT efficiency, are briefly demonstrated, and we highlight recent progression in the development of PS-containing gold nanocomposites for effective cancer therapy. |
format | Online Article Text |
id | pubmed-6403910 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-64039102019-04-02 Near-Infrared-Responsive Cancer Photothermal and Photodynamic Therapy Using Gold Nanoparticles Kim, Hyung Shik Lee, Dong Yun Polymers (Basel) Review Rapid growth of nanotechnology is one of the most quickly emerging tendencies in cancer therapy. Gold nanoparticles roused a distinctive interest in the field, due to their incomparable light-to-thermal energy conversion efficiency, and their ability to load and deliver a variety of anticancer drugs. Therefore, simultaneous photothermal (PTT) and photodynamic (PDT) cancer therapy is available by the role of the thermal agent of the gold nanoparticle itself and the drug delivery carrier for photosensitizer (PS) transport. In this review, the physical, chemical, and biological properties of gold nanoparticle, which can promote PTT and PDT efficiency, are briefly demonstrated, and we highlight recent progression in the development of PS-containing gold nanocomposites for effective cancer therapy. MDPI 2018-08-30 /pmc/articles/PMC6403910/ /pubmed/30960886 http://dx.doi.org/10.3390/polym10090961 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Kim, Hyung Shik Lee, Dong Yun Near-Infrared-Responsive Cancer Photothermal and Photodynamic Therapy Using Gold Nanoparticles |
title | Near-Infrared-Responsive Cancer Photothermal and Photodynamic Therapy Using Gold Nanoparticles |
title_full | Near-Infrared-Responsive Cancer Photothermal and Photodynamic Therapy Using Gold Nanoparticles |
title_fullStr | Near-Infrared-Responsive Cancer Photothermal and Photodynamic Therapy Using Gold Nanoparticles |
title_full_unstemmed | Near-Infrared-Responsive Cancer Photothermal and Photodynamic Therapy Using Gold Nanoparticles |
title_short | Near-Infrared-Responsive Cancer Photothermal and Photodynamic Therapy Using Gold Nanoparticles |
title_sort | near-infrared-responsive cancer photothermal and photodynamic therapy using gold nanoparticles |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403910/ https://www.ncbi.nlm.nih.gov/pubmed/30960886 http://dx.doi.org/10.3390/polym10090961 |
work_keys_str_mv | AT kimhyungshik nearinfraredresponsivecancerphotothermalandphotodynamictherapyusinggoldnanoparticles AT leedongyun nearinfraredresponsivecancerphotothermalandphotodynamictherapyusinggoldnanoparticles |