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Near-Infrared-Responsive Cancer Photothermal and Photodynamic Therapy Using Gold Nanoparticles

Rapid growth of nanotechnology is one of the most quickly emerging tendencies in cancer therapy. Gold nanoparticles roused a distinctive interest in the field, due to their incomparable light-to-thermal energy conversion efficiency, and their ability to load and deliver a variety of anticancer drugs...

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Detalles Bibliográficos
Autores principales: Kim, Hyung Shik, Lee, Dong Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403910/
https://www.ncbi.nlm.nih.gov/pubmed/30960886
http://dx.doi.org/10.3390/polym10090961
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author Kim, Hyung Shik
Lee, Dong Yun
author_facet Kim, Hyung Shik
Lee, Dong Yun
author_sort Kim, Hyung Shik
collection PubMed
description Rapid growth of nanotechnology is one of the most quickly emerging tendencies in cancer therapy. Gold nanoparticles roused a distinctive interest in the field, due to their incomparable light-to-thermal energy conversion efficiency, and their ability to load and deliver a variety of anticancer drugs. Therefore, simultaneous photothermal (PTT) and photodynamic (PDT) cancer therapy is available by the role of the thermal agent of the gold nanoparticle itself and the drug delivery carrier for photosensitizer (PS) transport. In this review, the physical, chemical, and biological properties of gold nanoparticle, which can promote PTT and PDT efficiency, are briefly demonstrated, and we highlight recent progression in the development of PS-containing gold nanocomposites for effective cancer therapy.
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spelling pubmed-64039102019-04-02 Near-Infrared-Responsive Cancer Photothermal and Photodynamic Therapy Using Gold Nanoparticles Kim, Hyung Shik Lee, Dong Yun Polymers (Basel) Review Rapid growth of nanotechnology is one of the most quickly emerging tendencies in cancer therapy. Gold nanoparticles roused a distinctive interest in the field, due to their incomparable light-to-thermal energy conversion efficiency, and their ability to load and deliver a variety of anticancer drugs. Therefore, simultaneous photothermal (PTT) and photodynamic (PDT) cancer therapy is available by the role of the thermal agent of the gold nanoparticle itself and the drug delivery carrier for photosensitizer (PS) transport. In this review, the physical, chemical, and biological properties of gold nanoparticle, which can promote PTT and PDT efficiency, are briefly demonstrated, and we highlight recent progression in the development of PS-containing gold nanocomposites for effective cancer therapy. MDPI 2018-08-30 /pmc/articles/PMC6403910/ /pubmed/30960886 http://dx.doi.org/10.3390/polym10090961 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Kim, Hyung Shik
Lee, Dong Yun
Near-Infrared-Responsive Cancer Photothermal and Photodynamic Therapy Using Gold Nanoparticles
title Near-Infrared-Responsive Cancer Photothermal and Photodynamic Therapy Using Gold Nanoparticles
title_full Near-Infrared-Responsive Cancer Photothermal and Photodynamic Therapy Using Gold Nanoparticles
title_fullStr Near-Infrared-Responsive Cancer Photothermal and Photodynamic Therapy Using Gold Nanoparticles
title_full_unstemmed Near-Infrared-Responsive Cancer Photothermal and Photodynamic Therapy Using Gold Nanoparticles
title_short Near-Infrared-Responsive Cancer Photothermal and Photodynamic Therapy Using Gold Nanoparticles
title_sort near-infrared-responsive cancer photothermal and photodynamic therapy using gold nanoparticles
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403910/
https://www.ncbi.nlm.nih.gov/pubmed/30960886
http://dx.doi.org/10.3390/polym10090961
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