Cargando…

Synthesis and Properties of Low-Molecular-Weight PEI-Based Lipopolymers for Delivery of DNA

Rapid enzymatic degradation and fragmentation during DNA administration can result in limited gene expression, and consequently, poor efficacy. It is necessary to use novel vectors for DNA delivery. Herein, we aimed to design useful carriers for enhancing transfection efficiency (TE). These lipopoly...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xun, Miao-Miao, Huang, Zheng, Xiao, Ya-Ping, Liu, Yan-Hong, Zhang, Ji, Zhang, Ju-Hui, Yu, Xiao-Qi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403936/ https://www.ncbi.nlm.nih.gov/pubmed/30960985 http://dx.doi.org/10.3390/polym10101060

Ejemplares similares

Safe and Effective Delivery of mRNA Using Modified PEI-Based Lipopolymers
por: Wang, Huijing, et al.
Publicado: (2023)

Aromatic Modification of Low Molecular Weight PEI for Enhanced Gene Delivery
por: Yu, Qing-Ying, et al.
Publicado: (2017)

Hybrid lipopolymer vesicle drug delivery and release systems
por: Reimhult, Erik, et al.
Publicado: (2021)

Diacetylenic lipids in the design of stable lipopolymers able to complex and protect plasmid DNA
por: Temprana, C. Facundo, et al.
Publicado: (2017)

PEG/PEI-functionalized single-walled carbon nanotubes as delivery carriers for doxorubicin: synthesis, characterization, and in vitro evaluation
por: Yang, Shuoye, et al.
Publicado: (2020)

Physisorbed Polymer-Tethered Lipid Bilayer with Lipopolymer Gradient
por: Lin, Yu-Hung, et al.
Publicado: (2012)

Anchoring Property of a Novel Hydrophilic Lipopolymer, HDAS-SHP, Post-Inserted in Preformed Liposomes
por: Mare, Rosario, et al.
Publicado: (2019)

Surface Modification of Liposomes by a Lipopolymer Targeting Prostate Specific Membrane Antigen for Theranostic Delivery in Prostate Cancer
por: Yari, Hooman, et al.
Publicado: (2019)

Chitosan-Crosslinked Low Molecular Weight PEI-Conjugated Iron Oxide Nanoparticle for Safe and Effective DNA Delivery to Breast Cancer Cells
por: Lin, Guanyou, et al.
Publicado: (2022)

Structure and dynamics of liposomes designed for drug delivery: coarse-grained molecular dynamics simulations to reveal the role of lipopolymer incorporation
por: Lemaalem, Mohammed, et al.
Publicado: (2020)

Amino Acid-Linked Low Molecular Weight Polyethylenimine for Improved Gene Delivery and Biocompatibility
por: Wu, Xiao-Ru, et al.
Publicado: (2020)

Folic Acid and PEI Modified Mesoporous Silica for Targeted Delivery of Curcumin
por: Sun, Xiaoxiao, et al.
Publicado: (2019)

Critical Length of PEG Grafts on lPEI/DNA Nanoparticles for Efficient in Vivo Delivery
por: Williford, John-Michael, et al.
Publicado: (2016)

Radiation-enhanced delivery of plasmid DNA to tumors utilizing a novel PEI polyplex
por: Appelbe, Oliver K., et al.
Publicado: (2017)

Plasmid-DNA Delivery by Covalently Functionalized PEI-SPIONs as a Potential ‘Magnetofection’ Agent
por: Stein, René, et al.
Publicado: (2022)

PLGA–PEI nanoparticles for gene delivery to pulmonary epithelium
por: Bivas-Benita, Maytal, et al.
Publicado: (2004)

Cyclodextrin-PEI-Tat Polymer as a Vector for Plasmid DNA Delivery to Placenta Mesenchymal Stem Cells
por: Lai, Wing-Fu, et al.
Publicado: (2011)

Linear and Branched PEIs (Polyethylenimines) and Their Property Space
por: Lungu, Claudiu N., et al.
Publicado: (2016)

Novel PEI/Poly-γ-Gutamic Acid Nanoparticles for High Efficient siRNA and Plasmid DNA Co-Delivery
por: Peng, Shu-Fen, et al.
Publicado: (2017)

Echogenic PEGylated PEI-Loaded Microbubble As Efficient Gene Delivery System
por: Liufu, Chun, et al.
Publicado: (2019)

Fluorescent PEI@Pd nanoclusters: facile synthesis and application
por: Wen, Wen, et al.
Publicado: (2021)

Ruthenium-containing supramolecular nanoparticles based on bipyridine-modified cyclodextrin and adamantyl PEI with DNA condensation properties
por: Yan, Fang, et al.
Publicado: (2018)

Two Major Archaeal Pseudomurein Endoisopeptidases: PeiW and PeiP
por: Visweswaran, Ganesh Ram R., et al.
Publicado: (2010)

Chitosan-PEI passivated carbon dots for plasmid DNA and miRNA-153 delivery in cancer cells
por: Thakur, Saloni, et al.
Publicado: (2023)

Controlled release of PEI/DNA complexes from mannose-bearing chitosan microspheres as a potent delivery system to enhance immune response to HBV DNA vaccine
por: Zhou, Xianfeng, et al.
Publicado: (2007)

Fluorinated PEG-PEI Coated Magnetic Nanoparticles for siRNA Delivery and CXCR4 Knockdown
por: Cao, Yixiang, et al.
Publicado: (2022)

Use of ultrasound to enhance PEI-mediated gene delivery in vivo on diabetic model
por: Bubnov, Rostyslav V, et al.
Publicado: (2014)

Preparation and Characterization of PLA-PEG-PLA/PEI/DNA Nanoparticles for Improvement of Transfection Efficiency and Controlled Release of DNA in Gene Delivery Systems
por: Amani, Amin, et al.
Publicado: (2019)

Cationic lipid-coated PEI/DNA polyplexes with improved efficiency and reduced cytotoxicity for gene delivery into mesenchymal stem cells
por: Song, Hongmei, et al.
Publicado: (2012)

FGF Receptor-Mediated Gene Delivery Using Ligands Coupled to PEI-β-CyD
por: Hu, Yiping, et al.
Publicado: (2012)

Biochemical Characterisation of Phage Pseudomurein Endoisopeptidases PeiW and PeiP Using Synthetic Peptides
por: Schofield, Linley R., et al.
Publicado: (2015)

Optimization of Processing Conditions and Mechanical Properties for PEEK/PEI Multilayered Blends
por: Toro, Sebastián Andrés, et al.
Publicado: (2022)

Differential intracellular distribution of DNA complexed with polyethylenimine (PEI) and PEI-polyarginine PTD influences exogenous gene expression within live COS-7 cells
por: Doyle, Stephen R, et al.
Publicado: (2007)

I. M. Pei : a profile in american architecture
por: Wiseman, Carter
Publicado: (1990)

Synthesis of Anion Exchange Membranes Containing PVDF/PES and Either PEI or Fumion(®)
por: Salazar-Gastelum, Luis Javier, et al.
Publicado: (2022)

Dual-degradable disulfide-containing PEI–Pluronic/DNA polyplexes: transfection efficiency and balancing protection and DNA release
por: Zhang, Lifen, et al.
Publicado: (2013)

Morphology, Structure and Function Characterization of PEI Modified Magnetic Nanoparticles Gene Delivery System
por: Zhao, Xiang, et al.
Publicado: (2014)

Polyethyleneimine (PEI) as a Polymer-Based Co-Delivery System for Breast Cancer Therapy
por: Fahira, Alistia Ilmiah, et al.
Publicado: (2022)

Antheraea pernyi Silk Fibroin-Coated PEI/DNA Complexes for Targeted Gene Delivery in HEK 293 and HCT 116 Cells
por: Liu, Yu, et al.
Publicado: (2014)

Pulmonary delivery of DNA vaccine constructs using deacylated PEI elicits immune responses and protects against viral challenge infection()
por: Mann, Jamie F.S., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_tfu42qngo684qcctf7s68b1uol