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Cell Membrane-Camouflaged Nanoparticles: A Promising Biomimetic Strategy for Cancer Theragnostics

Biomimetic functionalization of nanoparticles through camouflaging with cellular membranes has emerged as a promising strategy for cancer theragnostics. Cellular membranes used for camouflaging nanoparticles are generally isolated from blood cells, immune cells, cancer cells, and stem cells. The cam...

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Detalles Bibliográficos
Autores principales: Vijayan, Veena, Uthaman, Saji, Park, In-Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404000/
https://www.ncbi.nlm.nih.gov/pubmed/30960908
http://dx.doi.org/10.3390/polym10090983
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author Vijayan, Veena
Uthaman, Saji
Park, In-Kyu
author_facet Vijayan, Veena
Uthaman, Saji
Park, In-Kyu
author_sort Vijayan, Veena
collection PubMed
description Biomimetic functionalization of nanoparticles through camouflaging with cellular membranes has emerged as a promising strategy for cancer theragnostics. Cellular membranes used for camouflaging nanoparticles are generally isolated from blood cells, immune cells, cancer cells, and stem cells. The camouflaging strategy of wrapping nanoparticles with cellular membranes allows for superior tumor targeting through self-recognition, homotypic targeting and prolonged systematic circulation, thereby aiding in effective tumor therapy. In this review, we emphasized the various types of cellular membrane-camouflaged nanoparticles, their mechanisms in targeted therapy and various biomimetic strategies for anti-cancer therapy.
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spelling pubmed-64040002019-04-02 Cell Membrane-Camouflaged Nanoparticles: A Promising Biomimetic Strategy for Cancer Theragnostics Vijayan, Veena Uthaman, Saji Park, In-Kyu Polymers (Basel) Review Biomimetic functionalization of nanoparticles through camouflaging with cellular membranes has emerged as a promising strategy for cancer theragnostics. Cellular membranes used for camouflaging nanoparticles are generally isolated from blood cells, immune cells, cancer cells, and stem cells. The camouflaging strategy of wrapping nanoparticles with cellular membranes allows for superior tumor targeting through self-recognition, homotypic targeting and prolonged systematic circulation, thereby aiding in effective tumor therapy. In this review, we emphasized the various types of cellular membrane-camouflaged nanoparticles, their mechanisms in targeted therapy and various biomimetic strategies for anti-cancer therapy. MDPI 2018-09-03 /pmc/articles/PMC6404000/ /pubmed/30960908 http://dx.doi.org/10.3390/polym10090983 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Vijayan, Veena
Uthaman, Saji
Park, In-Kyu
Cell Membrane-Camouflaged Nanoparticles: A Promising Biomimetic Strategy for Cancer Theragnostics
title Cell Membrane-Camouflaged Nanoparticles: A Promising Biomimetic Strategy for Cancer Theragnostics
title_full Cell Membrane-Camouflaged Nanoparticles: A Promising Biomimetic Strategy for Cancer Theragnostics
title_fullStr Cell Membrane-Camouflaged Nanoparticles: A Promising Biomimetic Strategy for Cancer Theragnostics
title_full_unstemmed Cell Membrane-Camouflaged Nanoparticles: A Promising Biomimetic Strategy for Cancer Theragnostics
title_short Cell Membrane-Camouflaged Nanoparticles: A Promising Biomimetic Strategy for Cancer Theragnostics
title_sort cell membrane-camouflaged nanoparticles: a promising biomimetic strategy for cancer theragnostics
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404000/
https://www.ncbi.nlm.nih.gov/pubmed/30960908
http://dx.doi.org/10.3390/polym10090983
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