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Incorporation of Conductive Materials into Hydrogels for Tissue Engineering Applications

In the field of tissue engineering, conductive hydrogels have been the most effective biomaterials to mimic the biological and electrical properties of tissues in the human body. The main advantages of conductive hydrogels include not only their physical properties but also their adequate electrical...

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Detalles Bibliográficos
Autores principales: Min, Ji Hong, Patel, Madhumita, Koh, Won-Gun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404001/
https://www.ncbi.nlm.nih.gov/pubmed/30961003
http://dx.doi.org/10.3390/polym10101078
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author Min, Ji Hong
Patel, Madhumita
Koh, Won-Gun
author_facet Min, Ji Hong
Patel, Madhumita
Koh, Won-Gun
author_sort Min, Ji Hong
collection PubMed
description In the field of tissue engineering, conductive hydrogels have been the most effective biomaterials to mimic the biological and electrical properties of tissues in the human body. The main advantages of conductive hydrogels include not only their physical properties but also their adequate electrical properties, which provide electrical signals to cells efficiently. However, when introducing a conductive material into a non-conductive hydrogel, a conflicting relationship between the electrical and mechanical properties may develop. This review examines the strengths and weaknesses of the generation of conductive hydrogels using various conductive materials such as metal nanoparticles, carbons, and conductive polymers. The fabrication method of blending, coating, and in situ polymerization is also added. Furthermore, the applications of conductive hydrogel in cardiac tissue engineering, nerve tissue engineering, and bone tissue engineering and skin regeneration are discussed in detail.
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spelling pubmed-64040012019-04-02 Incorporation of Conductive Materials into Hydrogels for Tissue Engineering Applications Min, Ji Hong Patel, Madhumita Koh, Won-Gun Polymers (Basel) Review In the field of tissue engineering, conductive hydrogels have been the most effective biomaterials to mimic the biological and electrical properties of tissues in the human body. The main advantages of conductive hydrogels include not only their physical properties but also their adequate electrical properties, which provide electrical signals to cells efficiently. However, when introducing a conductive material into a non-conductive hydrogel, a conflicting relationship between the electrical and mechanical properties may develop. This review examines the strengths and weaknesses of the generation of conductive hydrogels using various conductive materials such as metal nanoparticles, carbons, and conductive polymers. The fabrication method of blending, coating, and in situ polymerization is also added. Furthermore, the applications of conductive hydrogel in cardiac tissue engineering, nerve tissue engineering, and bone tissue engineering and skin regeneration are discussed in detail. MDPI 2018-09-28 /pmc/articles/PMC6404001/ /pubmed/30961003 http://dx.doi.org/10.3390/polym10101078 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Min, Ji Hong
Patel, Madhumita
Koh, Won-Gun
Incorporation of Conductive Materials into Hydrogels for Tissue Engineering Applications
title Incorporation of Conductive Materials into Hydrogels for Tissue Engineering Applications
title_full Incorporation of Conductive Materials into Hydrogels for Tissue Engineering Applications
title_fullStr Incorporation of Conductive Materials into Hydrogels for Tissue Engineering Applications
title_full_unstemmed Incorporation of Conductive Materials into Hydrogels for Tissue Engineering Applications
title_short Incorporation of Conductive Materials into Hydrogels for Tissue Engineering Applications
title_sort incorporation of conductive materials into hydrogels for tissue engineering applications
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404001/
https://www.ncbi.nlm.nih.gov/pubmed/30961003
http://dx.doi.org/10.3390/polym10101078
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