Cargando…
Systemic Blockade of ACVR2B Ligands Protects Myocardium from Acute Ischemia-Reperfusion Injury
Activin A and myostatin, members of the transforming growth factor (TGF)-β superfamily of secreted factors, are potent negative regulators of muscle growth, but their contribution to myocardial ischemia-reperfusion (IR) injury is not known. The aim of this study was to investigate if activin 2B (ACV...
Autores principales: | Magga, Johanna, Vainio, Laura, Kilpiö, Teemu, Hulmi, Juha J., Taponen, Saija, Lin, Ruizhu, Räsänen, Markus, Szabó, Zoltán, Gao, Erhe, Rahtu-Korpela, Lea, Alakoski, Tarja, Ulvila, Johanna, Laitinen, Mika, Pasternack, Arja, Koch, Walter J., Alitalo, Kari, Kivelä, Riikka, Ritvos, Olli, Kerkelä, Risto |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404100/ https://www.ncbi.nlm.nih.gov/pubmed/30765322 http://dx.doi.org/10.1016/j.ymthe.2019.01.013 |
Ejemplares similares
-
GSK3β Serine 389 Phosphorylation Modulates Cardiomyocyte Hypertrophy and Ischemic Injury
por: Vainio, Laura, et al.
Publicado: (2021) -
Inhibition of cardiomyocyte Sprouty1 protects from cardiac ischemia–reperfusion injury
por: Alakoski, Tarja, et al.
Publicado: (2019) -
miR-1468-3p Promotes Aging-Related Cardiac Fibrosis
por: Lin, Ruizhu, et al.
Publicado: (2020) -
Vezf1 regulates cardiac structure and contractile function
por: Paavola, Jere, et al.
Publicado: (2020) -
Connective Tissue Growth Factor Inhibition Enhances Cardiac Repair and Limits Fibrosis After Myocardial Infarction
por: Vainio, Laura E., et al.
Publicado: (2019)