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Histone deacetylase inhibition by Entinostat for the prevention of electrical and structural remodeling in heart failure

BACKGROUND: The development of heart failure is accompanied by complex changes in cardiac electrophysiology and functional properties of cardiomyocytes and fibroblasts. Histone deacetylase (HDAC) inhibitors hold great promise for the pharmaceutical therapy of several malignant diseases. Here, we des...

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Detalles Bibliográficos
Autores principales:	Freundt, Johanna K., Frommeyer, Gerrit, Spieker, Tilmann, Wötzel, Fabian, Grotthoff, Jochen Schulze, Stypmann, Jörg, Hempel, Georg, Schäfers, Michael, Jacobs, Andreas H., Eckardt, Lars, Lange, Philipp S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404297/ https://www.ncbi.nlm.nih.gov/pubmed/30841920 http://dx.doi.org/10.1186/s40360-019-0294-x

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