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Mechanical and thermodynamic properties of Aβ(42), Aβ(40), and α-synuclein fibrils: a coarse-grained method to complement experimental studies

We perform molecular dynamics simulation on several relevant biological fibrils associated with neurodegenerative diseases such as Aβ(40), Aβ(42), and α-synuclein systems to obtain a molecular understanding and interpretation of nanomechanical characterization experiments. The computational method i...

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Detalles Bibliográficos
Autores principales:	Poma, Adolfo B, Guzman, Horacio V, Li, Mai Suan, Theodorakis, Panagiotis E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Beilstein-Institut 2019
Materias:	Full Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404408/ https://www.ncbi.nlm.nih.gov/pubmed/30873322 http://dx.doi.org/10.3762/bjnano.10.51

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