Cargando…
GLP‐1 Is a Coronary Artery Vasodilator in Humans
BACKGROUND: The mechanism underlying the beneficial cardiovascular effects of the incretin GLP‐1 (glucagon‐like peptide 1) and its analogues in humans is elusive. We hypothesized that activating receptors located on vascular smooth muscle cells to induce either peripheral or coronary vasodilatation...
Autores principales: | Clarke, Sophie J., Giblett, Joel P., Yang, Lucy L., Hubsch, Annette, Zhao, Tian, Aetesam‐ur‐Rahman, Muhammad, West, Nick E. J., O'Sullivan, Michael, Figg, Nichola, Bennett, Martin, Wewer Albrechtsen, Nicolai J., Deacon, Carolyn F., Cheriyan, Joseph, Hoole, Stephen P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404441/ https://www.ncbi.nlm.nih.gov/pubmed/30571482 http://dx.doi.org/10.1161/JAHA.118.010321 |
Ejemplares similares
-
GLP-1 vasodilatation in humans with coronary artery disease is not adenosine mediated
por: Aetesam-ur-Rahman, Muhammad, et al.
Publicado: (2021) -
Glucagon-Like Peptide-1–Mediated Cardioprotection Does Not Reduce Right Ventricular Stunning and Cumulative Ischemic Dysfunction After Coronary Balloon Occlusion
por: Giblett, Joel P., et al.
Publicado: (2019) -
Antagonizing somatostatin receptor subtype 2 and 5 reduces blood glucose in a gut- and GLP-1R–dependent manner
por: Jepsen, Sara L., et al.
Publicado: (2021) -
On the relationship between glucose absorption and glucose‐stimulated secretion of GLP‐1, neurotensin, and PYY from different intestinal segments in the rat
por: Kuhre, Rune E., et al.
Publicado: (2017) -
Glucagon‐like peptide‐1 acutely affects renal blood flow and urinary flow rate in spontaneously hypertensive rats despite significantly reduced renal expression of GLP‐1 receptors
por: Ronn, Jonas, et al.
Publicado: (2017)