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Ipsilateral motor evoked potentials in a patient with unihemispheric cortical atrophy due to Rasmussen encephalitis

The role of the ipsilaterally descending motor pathways in the recovery mechanisms after unilateral hemispheric damage is still poorly understood. Motor output reorganization was investigated in a 56-year-old male patient with acquired unilateral hemispheric atrophy due to Rasmussen encephalitis. In...

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Autores principales: Nardone, Raffaele, Langthaler, Patrick B., Orioli, Andrea, Versace, Viviana, Scarano, Giuditta Ilaria, Brigo, Francesco, Saltuari, Leopold, Carnicelli, Luca, Trinka, Eugen, Sebastianelli, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404490/
https://www.ncbi.nlm.nih.gov/pubmed/30762014
http://dx.doi.org/10.4103/1673-5374.250581
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author Nardone, Raffaele
Langthaler, Patrick B.
Orioli, Andrea
Versace, Viviana
Scarano, Giuditta Ilaria
Brigo, Francesco
Saltuari, Leopold
Carnicelli, Luca
Trinka, Eugen
Sebastianelli, Luca
author_facet Nardone, Raffaele
Langthaler, Patrick B.
Orioli, Andrea
Versace, Viviana
Scarano, Giuditta Ilaria
Brigo, Francesco
Saltuari, Leopold
Carnicelli, Luca
Trinka, Eugen
Sebastianelli, Luca
author_sort Nardone, Raffaele
collection PubMed
description The role of the ipsilaterally descending motor pathways in the recovery mechanisms after unilateral hemispheric damage is still poorly understood. Motor output reorganization was investigated in a 56-year-old male patient with acquired unilateral hemispheric atrophy due to Rasmussen encephalitis. In particular, the ipsilateral corticospinal pathways were explored using focal transcranial magnetic stimulation. In the first dorsal interosseous and wrist extensors muscles, the median amplitudes of the ipsilateral motor evoked potentials induced by transcranial magnetic stimulation in the patient were higher than those of 10 age-matched healthy control subjects. In the biceps brachii muscle, the median amplitudes of the ipsilateral motor evoked potentials were the second largest in the patient compared to the controls. This study demonstrated a reinforcement of ipsilateral motor projections from the unaffected motor cortex to the hemiparetic hand in a subject with acquired unihemispheric cortical damage.
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spelling pubmed-64044902019-06-01 Ipsilateral motor evoked potentials in a patient with unihemispheric cortical atrophy due to Rasmussen encephalitis Nardone, Raffaele Langthaler, Patrick B. Orioli, Andrea Versace, Viviana Scarano, Giuditta Ilaria Brigo, Francesco Saltuari, Leopold Carnicelli, Luca Trinka, Eugen Sebastianelli, Luca Neural Regen Res Research Article The role of the ipsilaterally descending motor pathways in the recovery mechanisms after unilateral hemispheric damage is still poorly understood. Motor output reorganization was investigated in a 56-year-old male patient with acquired unilateral hemispheric atrophy due to Rasmussen encephalitis. In particular, the ipsilateral corticospinal pathways were explored using focal transcranial magnetic stimulation. In the first dorsal interosseous and wrist extensors muscles, the median amplitudes of the ipsilateral motor evoked potentials induced by transcranial magnetic stimulation in the patient were higher than those of 10 age-matched healthy control subjects. In the biceps brachii muscle, the median amplitudes of the ipsilateral motor evoked potentials were the second largest in the patient compared to the controls. This study demonstrated a reinforcement of ipsilateral motor projections from the unaffected motor cortex to the hemiparetic hand in a subject with acquired unihemispheric cortical damage. Medknow Publications & Media Pvt Ltd 2019-06 /pmc/articles/PMC6404490/ /pubmed/30762014 http://dx.doi.org/10.4103/1673-5374.250581 Text en Copyright: © Neural Regeneration Research http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Research Article
Nardone, Raffaele
Langthaler, Patrick B.
Orioli, Andrea
Versace, Viviana
Scarano, Giuditta Ilaria
Brigo, Francesco
Saltuari, Leopold
Carnicelli, Luca
Trinka, Eugen
Sebastianelli, Luca
Ipsilateral motor evoked potentials in a patient with unihemispheric cortical atrophy due to Rasmussen encephalitis
title Ipsilateral motor evoked potentials in a patient with unihemispheric cortical atrophy due to Rasmussen encephalitis
title_full Ipsilateral motor evoked potentials in a patient with unihemispheric cortical atrophy due to Rasmussen encephalitis
title_fullStr Ipsilateral motor evoked potentials in a patient with unihemispheric cortical atrophy due to Rasmussen encephalitis
title_full_unstemmed Ipsilateral motor evoked potentials in a patient with unihemispheric cortical atrophy due to Rasmussen encephalitis
title_short Ipsilateral motor evoked potentials in a patient with unihemispheric cortical atrophy due to Rasmussen encephalitis
title_sort ipsilateral motor evoked potentials in a patient with unihemispheric cortical atrophy due to rasmussen encephalitis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404490/
https://www.ncbi.nlm.nih.gov/pubmed/30762014
http://dx.doi.org/10.4103/1673-5374.250581
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