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Genetic Variants Associated With Plasma Lipids Are Associated With the Lipid Response to Niacin

BACKGROUND: Niacin is a broad‐spectrum lipid‐modulating drug, but its mechanism of action is unclear. Genome‐wide association studies have identified multiple loci associated with blood lipid levels and lipoprotein (a). It is unknown whether these loci modulate response to niacin. METHODS AND RESULT...

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Detalles Bibliográficos
Autores principales:	Tuteja, Sony, Qu, Liming, Vujkovic, Marijana, Dunbar, Richard L., Chen, Jinbo, DerOhannessian, Stephanie, Rader, Daniel J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404865/ https://www.ncbi.nlm.nih.gov/pubmed/30371334 http://dx.doi.org/10.1161/JAHA.117.008461

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