Cargando…

A Robust and Efficient Numerical Method for RNA-Mediated Viral Dynamics

The multiscale model of hepatitis C virus (HCV) dynamics, which includes intracellular viral RNA (vRNA) replication, has been formulated in recent years in order to provide a new conceptual framework for understanding the mechanism of action of a variety of agents for the treatment of HCV. We presen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Reinharz, Vladimir, Churkin, Alexander, Dahari, Harel, Barash, Danny
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404971/ https://www.ncbi.nlm.nih.gov/pubmed/30854378 http://dx.doi.org/10.3389/fams.2017.00020

Ejemplares similares

Efficient Methods for Parameter Estimation of Ordinary and Partial Differential Equation Models of Viral Hepatitis Kinetics
por: Churkin, Alexander, et al.
Publicado: (2020)

Efficient procedures for the numerical simulation of mid-size RNA kinetics
por: Aviram, Iddo, et al.
Publicado: (2012)

Design of RNAs: comparing programs for inverse RNA folding
por: Churkin, Alexander, et al.
Publicado: (2017)

An efficient method for the prediction of deleterious multiple-point mutations in the secondary structure of RNAs using suboptimal folding solutions
por: Churkin, Alexander, et al.
Publicado: (2008)

Modeling-Based Response-Guided DAA Therapy for Chronic Hepatitis C to Identify Individuals for Shortening Treatment Duration
por: Goyal, Ashish, et al.
Publicado: (2022)

RNAmute: RNA secondary structure mutation analysis tool
por: Churkin, Alexander, et al.
Publicado: (2006)

The RNAmute web server for the mutational analysis of RNA secondary structures
por: Churkin, Alexander, et al.
Publicado: (2011)

RNAexinv: An extended inverse RNA folding from shape and physical attributes to sequences
por: Avihoo, Assaf, et al.
Publicado: (2011)

RNAthermsw: Direct Temperature Simulations for Predicting the Location of RNA Thermometers
por: Churkin, Alexander, et al.
Publicado: (2014)

IndelsRNAmute: predicting deleterious multiple point substitutions and indels mutations
por: Churkin, Alexander, et al.
Publicado: (2022)

incaRNAfbinv: a web server for the fragment-based design of RNA sequences
por: Drory Retwitzer, Matan, et al.
Publicado: (2016)

Modeling suggests that virion production cycles within individual cells is key to understanding acute hepatitis B virus infection kinetics
por: Hailegiorgis, Atesmachew, et al.
Publicado: (2023)

RNAPattMatch: a web server for RNA sequence/structure motif detection based on pattern matching with flexible gaps
por: Drory Retwitzer, Matan, et al.
Publicado: (2015)

Dynamic optimization of distributed biological systems using robust and efficient numerical techniques
por: Vilas, Carlos, et al.
Publicado: (2012)

In silico whole-genome screening for cancer-related single-nucleotide polymorphisms located in human mRNA untranslated regions
por: Aouacheria, Abdel, et al.
Publicado: (2007)

Prevalence of end of treatment RNA-positive/sustained viral response in HCV patients treated with sofosbuvir combination therapies
por: Malespin, Miguel, et al.
Publicado: (2016)

An Efficient Minimum Free Energy Structure-Based Search Method for Riboswitch Identification Based on Inverse RNA Folding
por: Drory Retwitzer, Matan, et al.
Publicado: (2015)

Numerical methods in fluid dynamics
por: Holt, Maurice
Publicado: (1977)

Numerical methods in fluid dynamics /
por: Holt, Maurice
Publicado: (1977)

Numerical methods in multibody dynamics
por: Eich-Soellner, Edda, et al.
Publicado: (1998)

Numerical methods in fluid dynamics
por: Holt, Maurice
Publicado: (1984)

Modeling Challenges of Ebola Virus–Host Dynamics during Infection and Treatment
por: Chertow, Daniel S., et al.
Publicado: (2020)

Accounting for Space — Quantification of Cell-To-Cell Transmission Kinetics Using Virus Dynamics Models
por: Kumberger, Peter, et al.
Publicado: (2018)

Numerical integration methods and layout improvements in the context of dynamic RNA visualization
por: Shabash, Boris, et al.
Publicado: (2017)

Designing transmissible viral vaccines for evolutionary robustness and maximum efficiency
por: Layman, Nathan C, et al.
Publicado: (2021)

Numerical methods to estimate the dynamic aperture
por: Giovannozzi, Massimo, et al.
Publicado: (1996)

Combining structure probing data on RNA mutants with evolutionary information reveals RNA-binding interfaces
por: Reinharz, Vladimir, et al.
Publicado: (2016)

Dynamical Systems Method and Applications: Theoretical Developments and Numerical Examples
por: Ramm, Alexander G, et al.
Publicado: (2012)

αβDCA method identifies unspecific binding but specific disruption of the group I intron by the StpA chaperone
por: Reinharz, Vladimir, et al.
Publicado: (2020)

Understanding the antiviral effects of RNAi-based therapy in HBeAg-positive chronic hepatitis B infection
por: Kadelka, Sarah, et al.
Publicado: (2021)

Cell-associated HIV RNA: a dynamic biomarker of viral persistence
por: Pasternak, Alexander O, et al.
Publicado: (2013)

On the emergence of structural complexity in RNA replicators
por: Oliver, Carlos G., et al.
Publicado: (2019)

Towards 3D structure prediction of large RNA molecules: an integer programming framework to insert local 3D motifs in RNA secondary structure
por: Reinharz, Vladimir, et al.
Publicado: (2012)

Molecular dynamics: with deterministic and stochastic numerical methods
por: Leimkuhler, Ben, et al.
Publicado: (2015)

Conference on Mathematical and numerical methods in fluid dynamics
por: International Centre for Theoretical Physics. Trieste
Publicado: (1976)

Numerical Methods for Fluid Dynamics: With Applications to Geophysics
por: Durran, Dale R
Publicado: (2010)

Quantum dynamic imaging: theoretical and numerical methods
por: Bandrauk, André D, et al.
Publicado: (2011)

CAMPAREE: a robust and configurable RNA expression simulator
por: Lahens, Nicholas F., et al.
Publicado: (2021)

RNA-MoIP: prediction of RNA secondary structure and local 3D motifs from sequence data
por: Yao, Jason, et al.
Publicado: (2017)

RNA-MoIP: prediction of RNA secondary structure and local 3D motifs from sequence data
por: Yao, Jason, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_1umh2q3vma45149h979pskrl6o