Genomic Characterization of Upper-Tract Urothelial Carcinoma in Patients With Lynch Syndrome

PURPOSE: Patients with Lynch syndrome (LS) have a significantly increased risk of developing upper-tract urothelial carcinoma (UTUC). Here, we sought to identify differences in the patterns of mutational changes in LS-associated versus sporadic UTUCs. PATIENTS AND METHODS: We performed targeted sequ...

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Detalles Bibliográficos
Autores principales: Donahue, Timothy F., Bagrodia, Aditya, Audenet, François, Donoghue, Mark T.A., Cha, Eugene K., Sfakianos, John P., Sperling, Dahlia, Al-Ahmadie, Hikmat, Clendenning, Mark, Rosty, Christophe, Buchanan, Daniel D., Jenkins, Mark, Hopper, John, Winship, Ingrid, Templeton, Allyson S., Walsh, Michael F., Stadler, Zsofia K., Iyer, Gopa, Taylor, Barry, Coleman, Jonathan, Lindor, Noralane M., Solit, David B., Bochner, Bernard H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Clinical Oncology 2018
Materias:
Original Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404976/
https://www.ncbi.nlm.nih.gov/pubmed/30854504
http://dx.doi.org/10.1200/PO.17.00143

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