Edition of TFAM gene by CRISPR/Cas9 technology in bovine model

The mitochondrial transcription factor A (TFAM) is a mitochondrial DNA (mtDNA) binding protein essential for the initiation of transcription and genome maintenance. Recently it was demonstrated that the primary role of TFAM is to maintain the integrity of mtDNA and that it is a key regulator of mtDN...

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Detalles Bibliográficos
Autores principales: de Oliveira, Vanessa Cristina, Moreira, Gabriel Sassarão Alves, Bressan, Fabiana Fernandes, Gomes Mariano Junior, Clésio, Roballo, Kelly Cristine Santos, Charpentier, Marine, Concordet, Jean-Paul, Meirelles, Flávio Vieira, Ambrósio, Carlos Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405117/
https://www.ncbi.nlm.nih.gov/pubmed/30845180
http://dx.doi.org/10.1371/journal.pone.0213376

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