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Maternal resistin predisposes offspring to hypothalamic inflammation and body weight gain

Resistin promotes hypothalamic neuroinflammation and insulin resistance through Toll like receptor 4 (TLR4), this hormone is thought to be a link between obesity and insulin-resistance. Indeed, resistin plasma levels are higher in obese and insulin resistant subjects. However, the impact of maternal...

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Detalles Bibliográficos
Autores principales: Poizat, Ghislaine, Alexandre, Coralie, Al Rifai, Sarah, Riffault, Laure, Crepin, Delphine, Benomar, Yacir, Taouis, Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405160/
https://www.ncbi.nlm.nih.gov/pubmed/30845245
http://dx.doi.org/10.1371/journal.pone.0213267