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The role of TLR9 on Leishmania amazonensis infection and its influence on intranasal LaAg vaccine efficacy

Leishmania (L.) amazonensis is one of the etiological agents of cutaneous leishmaniasis (CL) in Brazil. Currently, there is no vaccine approved for human use against leishmaniasis, although several vaccine preparations are in experimental stages. One of them is Leishvacin, or LaAg, a first-generatio...

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Detalles Bibliográficos
Autores principales: Pratti, Juliana Elena Silveira, da Fonseca Martins, Alessandra Marcia, da Silva, Juliana Paiva, Ramos, Tadeu Diniz, Pereira, Joyce Carvalho, Firmino-Cruz, Luan, Oliveira-Maciel, Diogo, Vieira, Thiago Soares de Souza, Lacerda, Leandra Linhares, Vale, Andre Macedo, Freire-de-Lima, Celio G., Gomes, Daniel C. Oliveira, Saraiva, Elvira M., Rossi-Bergmann, Bartira, de Matos Guedes, Herbert Leonel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405171/
https://www.ncbi.nlm.nih.gov/pubmed/30802247
http://dx.doi.org/10.1371/journal.pntd.0007146