Cargando…
Working memory improves developmentally as neural processes stabilize
Working memory performance is a key indicator of cognitive and developmental status. While recent evidence indicates that stabilizing neural gain supports the stabilization of working memory during adolescence, the computational mechanisms linking neural stabilization to behavior are poorly understo...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405198/ https://www.ncbi.nlm.nih.gov/pubmed/30845260 http://dx.doi.org/10.1371/journal.pone.0213010 |
_version_ | 1783401036967313408 |
---|---|
author | Montez, David Florentino Calabro, Finnegan J. Luna, Beatriz |
author_facet | Montez, David Florentino Calabro, Finnegan J. Luna, Beatriz |
author_sort | Montez, David Florentino |
collection | PubMed |
description | Working memory performance is a key indicator of cognitive and developmental status. While recent evidence indicates that stabilizing neural gain supports the stabilization of working memory during adolescence, the computational mechanisms linking neural stabilization to behavior are poorly understood. We develop a mechanistic account of behavior during the memory-guided saccade task based on a stochastic accumulator framework. Results indicate that a specific balance of independent gain signals affecting working memory representations and oculomotor response thresholds can account for a peculiar U-shaped feature of the speed-accuracy relationship. Additionally, aspects of behavioral variability and mean behavioral performance, as well as subtle shifts in the shape of the speed-accuracy relationship across development, can be accounted for by the stabilization of these two sources of variability. Thus, the stabilization of neural variability can, in part, account for developmental improvements in behavioral variability as well as some improvement in mean behavioral performance. |
format | Online Article Text |
id | pubmed-6405198 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-64051982019-03-17 Working memory improves developmentally as neural processes stabilize Montez, David Florentino Calabro, Finnegan J. Luna, Beatriz PLoS One Research Article Working memory performance is a key indicator of cognitive and developmental status. While recent evidence indicates that stabilizing neural gain supports the stabilization of working memory during adolescence, the computational mechanisms linking neural stabilization to behavior are poorly understood. We develop a mechanistic account of behavior during the memory-guided saccade task based on a stochastic accumulator framework. Results indicate that a specific balance of independent gain signals affecting working memory representations and oculomotor response thresholds can account for a peculiar U-shaped feature of the speed-accuracy relationship. Additionally, aspects of behavioral variability and mean behavioral performance, as well as subtle shifts in the shape of the speed-accuracy relationship across development, can be accounted for by the stabilization of these two sources of variability. Thus, the stabilization of neural variability can, in part, account for developmental improvements in behavioral variability as well as some improvement in mean behavioral performance. Public Library of Science 2019-03-07 /pmc/articles/PMC6405198/ /pubmed/30845260 http://dx.doi.org/10.1371/journal.pone.0213010 Text en © 2019 Montez et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Montez, David Florentino Calabro, Finnegan J. Luna, Beatriz Working memory improves developmentally as neural processes stabilize |
title | Working memory improves developmentally as neural processes stabilize |
title_full | Working memory improves developmentally as neural processes stabilize |
title_fullStr | Working memory improves developmentally as neural processes stabilize |
title_full_unstemmed | Working memory improves developmentally as neural processes stabilize |
title_short | Working memory improves developmentally as neural processes stabilize |
title_sort | working memory improves developmentally as neural processes stabilize |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405198/ https://www.ncbi.nlm.nih.gov/pubmed/30845260 http://dx.doi.org/10.1371/journal.pone.0213010 |
work_keys_str_mv | AT montezdavidflorentino workingmemoryimprovesdevelopmentallyasneuralprocessesstabilize AT calabrofinneganj workingmemoryimprovesdevelopmentallyasneuralprocessesstabilize AT lunabeatriz workingmemoryimprovesdevelopmentallyasneuralprocessesstabilize |