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Structural basis for KCTD-mediated rapid desensitization of GABA(B) signaling
The GABA(B) receptor is one of the principal inhibitory neurotransmitter receptors in the brain, and it signals through heterotrimeric G proteins to activate a variety of effectors including G protein-coupled inwardly-rectifying potassium channels (GIRKs)(1,2). GABA(B) receptor signaling is tightly...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405316/ https://www.ncbi.nlm.nih.gov/pubmed/30814734 http://dx.doi.org/10.1038/s41586-019-0990-0 |