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Epidemiology and disease characteristics of symptomatic choledocholithiasis in Sri Lanka

BACKGROUNDS/AIMS: Published data on choledocholithiasis in Sri Lanka is scarce. This study was conducted to determine epidemiological, clinical and endoscopic characteristics of choledocholithiasis in Sri Lanka. METHODS: This was a retrospective study of consecutive patients for a period of three ye...

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Autores principales: De Silva, Waduthanthri Supun Lakmal, Pathirana, Ajith Aloka, Wijerathne, Thejana Kamil, Gamage, Bawantha Dilshan, Dassanayake, Buddhika Kemiya, De Silva, Mohan Malith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Association of Hepato-Biliary-Pancreatic Surgery 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405359/
https://www.ncbi.nlm.nih.gov/pubmed/30863806
http://dx.doi.org/10.14701/ahbps.2019.23.1.41
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author De Silva, Waduthanthri Supun Lakmal
Pathirana, Ajith Aloka
Wijerathne, Thejana Kamil
Gamage, Bawantha Dilshan
Dassanayake, Buddhika Kemiya
De Silva, Mohan Malith
author_facet De Silva, Waduthanthri Supun Lakmal
Pathirana, Ajith Aloka
Wijerathne, Thejana Kamil
Gamage, Bawantha Dilshan
Dassanayake, Buddhika Kemiya
De Silva, Mohan Malith
author_sort De Silva, Waduthanthri Supun Lakmal
collection PubMed
description BACKGROUNDS/AIMS: Published data on choledocholithiasis in Sri Lanka is scarce. This study was conducted to determine epidemiological, clinical and endoscopic characteristics of choledocholithiasis in Sri Lanka. METHODS: This was a retrospective study of consecutive patients for a period of three years until April 2016. The sample included patients from many parts of the island. Patients were selected from the endoscopy database of the unit and the data were collected from the records of the patients. RESULTS: A total of 253 patients were included in the study. The mean age of the patients was 53.6 years. Patients presented with obstructive jaundice (58.5%), cholangitis (25.3%), biliary colic or upper abdominal pain (14.2%) and acute biliary pancreatitis (1.8%). There were 26 (10.3%) post cholecystectomy patients. Concomitant gallbladder stones were found in 173 patients (68.4%). Juxta-papillary diverticula were found in 36 patients (14.2%). Twenty-one (8.3%) and nine patients (3.6%) were found to have choledochal cysts and common bile duct strictures, respectively. Stones were commonly found in the distal common bile duct (68.4%). A majority of the patients had a single stone (47.8%). In 209 patients (79.6%), the size of the largest stones measured between 0.5–1.5 cm. CONCLUSIONS: Choledocholithiasis is a disease affecting middle-aged population with predominance among females in Sri Lanka. Patients with symptomatic choledocholithiasis commonly present with obstructive jaundice. In the present study, most of the stones were formed in anatomically normal biliary systems. Stones were predominantly distal, single and measured 0.5–1.5 cm in size. The observed features were favorable features for successful endoscopic clearance. None of the patients included in the study had primary CBD stones according to the available criteria.
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spelling pubmed-64053592019-03-12 Epidemiology and disease characteristics of symptomatic choledocholithiasis in Sri Lanka De Silva, Waduthanthri Supun Lakmal Pathirana, Ajith Aloka Wijerathne, Thejana Kamil Gamage, Bawantha Dilshan Dassanayake, Buddhika Kemiya De Silva, Mohan Malith Ann Hepatobiliary Pancreat Surg Original Article BACKGROUNDS/AIMS: Published data on choledocholithiasis in Sri Lanka is scarce. This study was conducted to determine epidemiological, clinical and endoscopic characteristics of choledocholithiasis in Sri Lanka. METHODS: This was a retrospective study of consecutive patients for a period of three years until April 2016. The sample included patients from many parts of the island. Patients were selected from the endoscopy database of the unit and the data were collected from the records of the patients. RESULTS: A total of 253 patients were included in the study. The mean age of the patients was 53.6 years. Patients presented with obstructive jaundice (58.5%), cholangitis (25.3%), biliary colic or upper abdominal pain (14.2%) and acute biliary pancreatitis (1.8%). There were 26 (10.3%) post cholecystectomy patients. Concomitant gallbladder stones were found in 173 patients (68.4%). Juxta-papillary diverticula were found in 36 patients (14.2%). Twenty-one (8.3%) and nine patients (3.6%) were found to have choledochal cysts and common bile duct strictures, respectively. Stones were commonly found in the distal common bile duct (68.4%). A majority of the patients had a single stone (47.8%). In 209 patients (79.6%), the size of the largest stones measured between 0.5–1.5 cm. CONCLUSIONS: Choledocholithiasis is a disease affecting middle-aged population with predominance among females in Sri Lanka. Patients with symptomatic choledocholithiasis commonly present with obstructive jaundice. In the present study, most of the stones were formed in anatomically normal biliary systems. Stones were predominantly distal, single and measured 0.5–1.5 cm in size. The observed features were favorable features for successful endoscopic clearance. None of the patients included in the study had primary CBD stones according to the available criteria. Korean Association of Hepato-Biliary-Pancreatic Surgery 2019-02 2019-02-28 /pmc/articles/PMC6405359/ /pubmed/30863806 http://dx.doi.org/10.14701/ahbps.2019.23.1.41 Text en Copyright © 2019 by The Korean Association of Hepato-Biliary-Pancreatic Surgery http://creativecommons.org/licenses/by-nc/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
De Silva, Waduthanthri Supun Lakmal
Pathirana, Ajith Aloka
Wijerathne, Thejana Kamil
Gamage, Bawantha Dilshan
Dassanayake, Buddhika Kemiya
De Silva, Mohan Malith
Epidemiology and disease characteristics of symptomatic choledocholithiasis in Sri Lanka
title Epidemiology and disease characteristics of symptomatic choledocholithiasis in Sri Lanka
title_full Epidemiology and disease characteristics of symptomatic choledocholithiasis in Sri Lanka
title_fullStr Epidemiology and disease characteristics of symptomatic choledocholithiasis in Sri Lanka
title_full_unstemmed Epidemiology and disease characteristics of symptomatic choledocholithiasis in Sri Lanka
title_short Epidemiology and disease characteristics of symptomatic choledocholithiasis in Sri Lanka
title_sort epidemiology and disease characteristics of symptomatic choledocholithiasis in sri lanka
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405359/
https://www.ncbi.nlm.nih.gov/pubmed/30863806
http://dx.doi.org/10.14701/ahbps.2019.23.1.41
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