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Autotaxin and Lipoprotein Metabolism in Calcific Aortic Valve Disease

Calcific aortic valve disease (CAVD) is a complex trait disorder characterized by calcific remodeling of leaflets. Genome-wide association (GWA) study and Mendelian randomization (MR) have highlighted that LPA, which encodes for apolipoprotein(a) [apo(a)], is causally associated with CAVD. Apo(a) is...

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Detalles Bibliográficos
Autores principales: Mathieu, Patrick, Boulanger, Marie-Chloé
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405425/
https://www.ncbi.nlm.nih.gov/pubmed/30881959
http://dx.doi.org/10.3389/fcvm.2019.00018

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