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27-Hydroxycholesterol Contributes to Lysosomal Membrane Permeabilization-Mediated Pyroptosis in Co-cultured SH-SY5Y Cells and C6 Cells
Purpose: Emerging evidence suggests that 27-Hydroxycholesterol (27-OHC) causes neurodegenerative diseases through the induction of cytotoxicity and cholesterol metabolism disorder. The objective of this study is to determine the impacts of 27-OHC on lysosomal membrane permeabilization (LMP) and pyro...
Autores principales: | Chen, Si, Zhou, Cui, Yu, Huiyan, Tao, Lingwei, An, Yu, Zhang, Xiaona, Wang, Ying, Wang, Yushan, Xiao, Rong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405519/ https://www.ncbi.nlm.nih.gov/pubmed/30881285 http://dx.doi.org/10.3389/fnmol.2019.00014 |
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