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Metoprolol Inhibits Profibrotic Remodeling of Epicardial Adipose Tissue in a Canine Model of Chronic Obstructive Sleep Apnea

BACKGROUND: Whether chronic obstructive sleep apnea (OSA) could promote epicardial adipose tissue (EAT) secretion of profibrotic adipokines, and thereby contribute to atrial fibrosis, and the potential therapeutic effects of metoprolol remain unknown. METHODS AND RESULTS: A chronic OSA canine model...

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Detalles Bibliográficos
Autores principales:	Dai, Hui, Yuan, Yue, Yin, Shuangli, Zhang, Yun, Han, Yu, Sun, Li, Li, Tiankai, Xu, Jicheng, Sheng, Li, Gong, Yongtai, Li, Yue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405574/ https://www.ncbi.nlm.nih.gov/pubmed/30686096 http://dx.doi.org/10.1161/JAHA.118.011155

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