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Live-Imaging Readouts and Cell Models for Phenotypic Profiling of Mitochondrial Function

Mitochondria are best known as the powerhouses of the cells but their cellular role goes far beyond energy production; among others, they have a pivotal function in cellular calcium and redox homeostasis. Mitochondrial dysfunction is often associated with severe and relatively rare disorders with an...

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Detalles Bibliográficos
Autores principales: Iannetti, Eligio F., Prigione, Alessandro, Smeitink, Jan A. M., Koopman, Werner J. H., Beyrath, Julien, Renkema, Herma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405630/
https://www.ncbi.nlm.nih.gov/pubmed/30881379
http://dx.doi.org/10.3389/fgene.2019.00131