Cargando…

The Impact of Heterogeneity on Single-Cell Sequencing

The importance of diversity and cellular specialization is clear for many reasons, from population-level diversification, to improved resiliency to unforeseen stresses, to unique functions within metazoan organisms during development and differentiation. However, the level of cellular heterogeneity...

Descripción completa

Detalles Bibliográficos
Autores principales:	Goldman, Samantha L., MacKay, Matthew, Afshinnekoo, Ebrahim, Melnick, Ari M., Wu, Shuxiu, Mason, Christopher E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405636/ https://www.ncbi.nlm.nih.gov/pubmed/30881372 http://dx.doi.org/10.3389/fgene.2019.00008

Ejemplares similares

Epigenetic Modifications in Acute Myeloid Leukemia: Prognosis, Treatment, and Heterogeneity
por: Goldman, Samantha L., et al.
Publicado: (2019)

Multi-omic, Single-Cell, and Biochemical Profiles of Astronauts Guide Pharmacological Strategies for Returning to Gravity
por: Gertz, Monica L., et al.
Publicado: (2020)

Enhanced Reduced Representation Bisulfite Sequencing for Assessment of DNA Methylation at Base Pair Resolution
por: Garrett-Bakelman, Francine E., et al.
Publicado: (2015)

Single-Cell RNA Sequencing-Based Computational Analysis to Describe Disease Heterogeneity
por: Zeng, Tao, et al.
Publicado: (2019)

Single-cell RNA Sequencing Reveals Heterogeneity of Cultured Bovine Satellite Cells
por: Lyu, Pengcheng, et al.
Publicado: (2021)

Single-Cell RNA Sequencing Reveals Smooth Muscle Cells Heterogeneity in Experimental Aortic Dissection
por: Xu, Cheng, et al.
Publicado: (2022)

Long Read Single-Molecule Real-Time Sequencing Elucidates Transcriptome-Wide Heterogeneity and Complexity in Esophageal Squamous Cells
por: Cheng, Yin-Wei, et al.
Publicado: (2019)

Single-cell RNA sequencing analysis to explore immune cell heterogeneity and novel biomarkers for the prognosis of lung adenocarcinoma
por: Xu, Yong, et al.
Publicado: (2022)

Clonal Hematopoiesis Before, During, and After Human Spaceflight
por: Mencia-Trinchant, Nuria, et al.
Publicado: (2020)

Long-term spaceflight and the cardiovascular system
por: Vernice, Nicholas A, et al.
Publicado: (2020)

Single-cell RNA sequencing reveals intratumoral heterogeneity and potential mechanisms of malignant progression in prostate cancer with perineural invasion
por: Zhang, Bao, et al.
Publicado: (2023)

A high-efficiency differential expression method for cancer heterogeneity using large-scale single-cell RNA-sequencing data
por: Yuan, Xin, et al.
Publicado: (2022)

Genomic and Phenotypic Heterogeneity of Clinical Isolates of the Human Pathogens Aspergillus fumigatus, Aspergillus lentulus, and Aspergillus fumigatiaffinis
por: dos Santos, Renato A. C., et al.
Publicado: (2020)

Comprehensive analysis of mitophagy-related genes in diagnosis and heterogeneous endothelial cells in chronic rhinosinusitis: based on bulk and single-cell RNA sequencing data
por: Zhou, Shican, et al.
Publicado: (2023)

Concordant and Heterogeneity of Single-Cell Transcriptome in Cardiac Development of Human and Mouse
por: Shang, Mengyue, et al.
Publicado: (2022)

Heterogeneous Skeletal Muscle Cell and Nucleus Populations Identified by Single-Cell and Single-Nucleus Resolution Transcriptome Assays
por: Williams, Katherine, et al.
Publicado: (2022)

High Genetic Heterogeneity in Chinese Patients With Waardenburg Syndrome Revealed by Next-Generation Sequencing
por: Zhang, Sen, et al.
Publicado: (2021)

Unraveling Heterogeneity in Transcriptome and Its Regulation Through Single-Cell Multi-Omics Technologies
por: Xing, Qiao Rui, et al.
Publicado: (2020)

Single-Cell Transcriptomics Uncovers Cellular Heterogeneity, Mechanisms, and Therapeutic Targets for Parkinson’s Disease
por: Huang, Jianjun, et al.
Publicado: (2022)

On the optimal trimming of high-throughput mRNA sequence data
por: MacManes, Matthew D.
Publicado: (2014)

Quantifying the impact of inter-site heterogeneity on the distribution of ChIP-seq data
por: Cairns, Jonathan, et al.
Publicado: (2014)

Detection of Copy Number Alterations Using Single Cell Sequencing
por: Knouse, Kristin A., et al.
Publicado: (2017)

Mitochondrial Heterogeneity
por: Aryaman, Juvid, et al.
Publicado: (2019)

Assessing the Impact of Sample Heterogeneity on Transcriptome Analysis of Human Diseases Using MDP Webtool
por: Gonçalves, André N. A., et al.
Publicado: (2019)

Reference Transcriptomes of Porcine Peripheral Immune Cells Created Through Bulk and Single-Cell RNA Sequencing
por: Herrera-Uribe, Juber, et al.
Publicado: (2021)

Single-cell sequencing technologies in bladder cancer research: Applications and challenges
por: Lyu, Tianqi, et al.
Publicado: (2022)

Re-analysis of Whole Genome Sequence Data From 279 Ancient Eurasians Reveals Substantial Ancestral Heterogeneity
por: Shriner, Daniel
Publicado: (2018)

Prognostic Significance of Lineage Diversity in Bladder Cancer Revealed by Single-Cell Sequencing
por: Yu, Lu, et al.
Publicado: (2022)

Origin Sample Prediction and Spatial Modeling of Antimicrobial Resistance in Metagenomic Sequencing Data
por: Zhelyazkova, Maya, et al.
Publicado: (2021)

Editorial: Methods for Single-Cell and Microbiome Sequencing Data
por: Mallick, Himel, et al.
Publicado: (2022)

Missing Value Imputation With Low-Rank Matrix Completion in Single-Cell RNA-Seq Data by Considering Cell Heterogeneity
por: Huang, Meng, et al.
Publicado: (2022)

Heterogeneity of the Pancreatic Beta Cell
por: Gutierrez, Giselle Dominguez, et al.
Publicado: (2017)

What Is the Impact of mRNA 5′ TL Heterogeneity on Translational Start Site Selection and the Mammalian Cellular Phenotype?
por: Curran, Joseph A., et al.
Publicado: (2016)

Advances in single-cell sequencing technology in the field of hepatocellular carcinoma
por: Qin, Rongyi, et al.
Publicado: (2022)

Editorial: Statistical and computational methods for single-cell sequencing analysis
por: Hou, Lin, et al.
Publicado: (2023)

Heterogeneity in Metabolic Responses to Dietary Fructose
por: Hou, Ruixue, et al.
Publicado: (2019)

Spatial Transcriptomics for Tumor Heterogeneity Analysis
por: Li, Qiongyu, et al.
Publicado: (2022)

Genetic heterogeneity in corpus callosum agenesis
por: Pânzaru, Monica-Cristina, et al.
Publicado: (2022)

Exploring the Impact of Single-Nucleotide Polymorphisms on Translation
por: Robert, Francis, et al.
Publicado: (2018)

Exploration the global single-cell ecological landscape of adenomyosis-related cell clusters by single-cell RNA sequencing
por: Lin, Jiajing, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ut86tvlb8n38i2uj9to9d5bq5f