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Complex Role for E‐Prostanoid 4 Receptors in Hypertension

BACKGROUND: Prostaglandin E(2) (PGE (2)) is a major prostanoid with multiple actions that potentially affect blood pressure (BP). PGE (2) acts through 4 distinct E‐prostanoid (EP) receptor isoforms: EP1 to EP4. The EP4 receptor (EP4R) promotes PGE (2)‐dependent vasodilation, but its role in the path...

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Detalles Bibliográficos
Autores principales:	Herrera, Marcela, Yang, Ting, Sparks, Matthew A., Manning, Michael W., Koller, Beverly H., Coffman, Thomas M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405651/ https://www.ncbi.nlm.nih.gov/pubmed/30764697 http://dx.doi.org/10.1161/JAHA.118.010745

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