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MG53 Protein Protects Aortic Valve Interstitial Cells From Membrane Injury and Fibrocalcific Remodeling

BACKGROUND: The aortic valve of the heart experiences constant mechanical stress under physiological conditions. Maladaptive valve injury responses contribute to the development of valvular heart disease. Here, we test the hypothesis that MG53 (mitsugumin 53), an essential cell membrane repair prote...

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Detalles Bibliográficos
Autores principales:	Adesanya, T. M. Ayodele, Russell, Melanie, Park, Ki Ho, Zhou, Xinyu, Sermersheim, Matthew A., Gumpper, Kristyn, Koenig, Sara N., Tan, Tao, Whitson, Bryan A., Janssen, Paul M. L., Lincoln, Joy, Zhu, Hua, Ma, Jianjie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405656/ https://www.ncbi.nlm.nih.gov/pubmed/30741589 http://dx.doi.org/10.1161/JAHA.118.009960

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