Cargando…

Risk of Atrial Fibrillation in Black Versus White Medicare Beneficiaries With Implanted Cardiac Devices

BACKGROUND: Black individuals in the United States experience higher rates of ischemic stroke than other racial groups but have lower rates of clinically apparent atrial fibrillation (AF). It is unclear whether blacks truly have less AF or simply more undiagnosed AF. METHODS AND RESULTS: We performe...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Monica L., Parikh, Neal S., Merkler, Alexander E., Kleindorfer, Dawn O., Bhave, Prashant D., Levitan, Emily B., Soliman, Elsayed Z., Kamel, Hooman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405685/
https://www.ncbi.nlm.nih.gov/pubmed/30741594
http://dx.doi.org/10.1161/JAHA.118.010661
_version_ 1783401134868660224
author Chen, Monica L.
Parikh, Neal S.
Merkler, Alexander E.
Kleindorfer, Dawn O.
Bhave, Prashant D.
Levitan, Emily B.
Soliman, Elsayed Z.
Kamel, Hooman
author_facet Chen, Monica L.
Parikh, Neal S.
Merkler, Alexander E.
Kleindorfer, Dawn O.
Bhave, Prashant D.
Levitan, Emily B.
Soliman, Elsayed Z.
Kamel, Hooman
author_sort Chen, Monica L.
collection PubMed
description BACKGROUND: Black individuals in the United States experience higher rates of ischemic stroke than other racial groups but have lower rates of clinically apparent atrial fibrillation (AF). It is unclear whether blacks truly have less AF or simply more undiagnosed AF. METHODS AND RESULTS: We performed a retrospective cohort study using inpatient and outpatient claims from 2009 to 2015 for a 5% nationally representative sample of Medicare beneficiaries. We included patients aged ≥66 years with at least 1 documented Current Procedural Terminology code for interrogation of an implantable pacemaker, cardioverter‐defibrillator, or loop recorder and no documented history of AF, atrial flutter, or stroke before their first device interrogation. Kaplan–Meier statistics and Cox proportional hazards models were used to examine the association between black race and the composite outcome of AF or atrial flutter while adjusting for age, sex, and vascular risk factors. Among 47 417 eligible patients, the annual incidence of AF/atrial flutter was 12.2 (95% CI, 11.5–13.1) per 100 person‐years among blacks and 17.6 (95% CI, 17.4–17.9) per 100 person‐years among non‐black beneficiaries. After adjustment for confounders, black beneficiaries faced a lower hazard of AF/atrial flutter than non‐black beneficiaries (hazard ratio, 0.75; 95% CI, 0.70–0.80). Despite the lower risk of AF, black patients faced a higher hazard of ischemic stroke (hazard ratio, 1.37; 95% CI, 1.22–1.53). CONCLUSIONS: Among Medicare beneficiaries with implanted cardiac devices capable of detecting atrial rhythm, black patients had a lower incidence of AF despite a higher burden of vascular risk factors and a higher risk of stroke.
format Online
Article
Text
id pubmed-6405685
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-64056852019-03-19 Risk of Atrial Fibrillation in Black Versus White Medicare Beneficiaries With Implanted Cardiac Devices Chen, Monica L. Parikh, Neal S. Merkler, Alexander E. Kleindorfer, Dawn O. Bhave, Prashant D. Levitan, Emily B. Soliman, Elsayed Z. Kamel, Hooman J Am Heart Assoc Original Research BACKGROUND: Black individuals in the United States experience higher rates of ischemic stroke than other racial groups but have lower rates of clinically apparent atrial fibrillation (AF). It is unclear whether blacks truly have less AF or simply more undiagnosed AF. METHODS AND RESULTS: We performed a retrospective cohort study using inpatient and outpatient claims from 2009 to 2015 for a 5% nationally representative sample of Medicare beneficiaries. We included patients aged ≥66 years with at least 1 documented Current Procedural Terminology code for interrogation of an implantable pacemaker, cardioverter‐defibrillator, or loop recorder and no documented history of AF, atrial flutter, or stroke before their first device interrogation. Kaplan–Meier statistics and Cox proportional hazards models were used to examine the association between black race and the composite outcome of AF or atrial flutter while adjusting for age, sex, and vascular risk factors. Among 47 417 eligible patients, the annual incidence of AF/atrial flutter was 12.2 (95% CI, 11.5–13.1) per 100 person‐years among blacks and 17.6 (95% CI, 17.4–17.9) per 100 person‐years among non‐black beneficiaries. After adjustment for confounders, black beneficiaries faced a lower hazard of AF/atrial flutter than non‐black beneficiaries (hazard ratio, 0.75; 95% CI, 0.70–0.80). Despite the lower risk of AF, black patients faced a higher hazard of ischemic stroke (hazard ratio, 1.37; 95% CI, 1.22–1.53). CONCLUSIONS: Among Medicare beneficiaries with implanted cardiac devices capable of detecting atrial rhythm, black patients had a lower incidence of AF despite a higher burden of vascular risk factors and a higher risk of stroke. John Wiley and Sons Inc. 2019-02-12 /pmc/articles/PMC6405685/ /pubmed/30741594 http://dx.doi.org/10.1161/JAHA.118.010661 Text en © 2019 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Original Research
Chen, Monica L.
Parikh, Neal S.
Merkler, Alexander E.
Kleindorfer, Dawn O.
Bhave, Prashant D.
Levitan, Emily B.
Soliman, Elsayed Z.
Kamel, Hooman
Risk of Atrial Fibrillation in Black Versus White Medicare Beneficiaries With Implanted Cardiac Devices
title Risk of Atrial Fibrillation in Black Versus White Medicare Beneficiaries With Implanted Cardiac Devices
title_full Risk of Atrial Fibrillation in Black Versus White Medicare Beneficiaries With Implanted Cardiac Devices
title_fullStr Risk of Atrial Fibrillation in Black Versus White Medicare Beneficiaries With Implanted Cardiac Devices
title_full_unstemmed Risk of Atrial Fibrillation in Black Versus White Medicare Beneficiaries With Implanted Cardiac Devices
title_short Risk of Atrial Fibrillation in Black Versus White Medicare Beneficiaries With Implanted Cardiac Devices
title_sort risk of atrial fibrillation in black versus white medicare beneficiaries with implanted cardiac devices
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405685/
https://www.ncbi.nlm.nih.gov/pubmed/30741594
http://dx.doi.org/10.1161/JAHA.118.010661
work_keys_str_mv AT chenmonical riskofatrialfibrillationinblackversuswhitemedicarebeneficiarieswithimplantedcardiacdevices
AT parikhneals riskofatrialfibrillationinblackversuswhitemedicarebeneficiarieswithimplantedcardiacdevices
AT merkleralexandere riskofatrialfibrillationinblackversuswhitemedicarebeneficiarieswithimplantedcardiacdevices
AT kleindorferdawno riskofatrialfibrillationinblackversuswhitemedicarebeneficiarieswithimplantedcardiacdevices
AT bhaveprashantd riskofatrialfibrillationinblackversuswhitemedicarebeneficiarieswithimplantedcardiacdevices
AT levitanemilyb riskofatrialfibrillationinblackversuswhitemedicarebeneficiarieswithimplantedcardiacdevices
AT solimanelsayedz riskofatrialfibrillationinblackversuswhitemedicarebeneficiarieswithimplantedcardiacdevices
AT kamelhooman riskofatrialfibrillationinblackversuswhitemedicarebeneficiarieswithimplantedcardiacdevices