Cryo-EM fibril structures from systemic AA amyloidosis reveal the species complementarity of pathological amyloids

Systemic AA amyloidosis is a worldwide occurring protein misfolding disease of humans and animals. It arises from the formation of amyloid fibrils from the acute phase protein serum amyloid A. Here, we report the purification and electron cryo-microscopy analysis of amyloid fibrils from a mouse and...

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Detalles Bibliográficos
Autores principales: Liberta, Falk, Loerch, Sarah, Rennegarbe, Matthies, Schierhorn, Angelika, Westermark, Per, Westermark, Gunilla T., Hazenberg, Bouke P. C., Grigorieff, Nikolaus, Fändrich, Marcus, Schmidt, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405766/
https://www.ncbi.nlm.nih.gov/pubmed/30846696
http://dx.doi.org/10.1038/s41467-019-09033-z

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