Targeted drug delivery via caveolae-associated protein PV1 improves lung fibrosis

Systemic administration of bio-therapeutics can result in only a fraction of drug reaching targeted tissues, with the majority of drug being distributed to tissues irrelevant to the drug’s site of action. Targeted delivery to specific organs may allow for greater accumulation, better efficacy, and i...

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Detalles Bibliográficos
Autores principales: Marchetti, Gabriela M., Burwell, Timothy J., Peterson, Norman C., Cann, Jennifer A., Hanna, Richard N., Li, Qing, Ongstad, Emily L., Boyd, Jonathan T., Kennedy, Maureen A., Zhao, Weiguang, Rickert, Keith W., Grimsby, Joseph S., Dall’Acqua, William F., Wu, Herren, Tsui, Ping, Borrok, M. Jack, Gupta, Ruchi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405929/
https://www.ncbi.nlm.nih.gov/pubmed/30854484
http://dx.doi.org/10.1038/s42003-019-0337-2

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