Multi-scale stochastic organization-oriented coarse-graining exemplified on the human mitotic checkpoint

The complexity of biological models makes methods for their analysis and understanding highly desirable. Here, we demonstrate the orchestration of various novel coarse-graining methods by applying them to the mitotic spindle assembly checkpoint. We begin with a detailed fine-grained spatial model in...

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Detalles Bibliográficos
Autores principales: Henze, Richard, Mu, Chunyan, Puljiz, Mate, Kamaleson, Nishanthan, Huwald, Jan, Haslegrave, John, di Fenizio, Pietro Speroni, Parker, David, Good, Christopher, Rowe, Jonathan E., Ibrahim, Bashar, Dittrich, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405958/
https://www.ncbi.nlm.nih.gov/pubmed/30846816
http://dx.doi.org/10.1038/s41598-019-40648-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405958/
https://www.ncbi.nlm.nih.gov/pubmed/30846816
http://dx.doi.org/10.1038/s41598-019-40648-w

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