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Multi-scale stochastic organization-oriented coarse-graining exemplified on the human mitotic checkpoint
The complexity of biological models makes methods for their analysis and understanding highly desirable. Here, we demonstrate the orchestration of various novel coarse-graining methods by applying them to the mitotic spindle assembly checkpoint. We begin with a detailed fine-grained spatial model in...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405958/ https://www.ncbi.nlm.nih.gov/pubmed/30846816 http://dx.doi.org/10.1038/s41598-019-40648-w |