Cargando…
Binding kinetics of ligands acting at GPCRs
The influence of drug-receptor binding kinetics has often been overlooked during the development of new therapeutics that target G protein-coupled receptors (GPCRs). Over the last decade there has been a growing understanding that an in-depth knowledge of binding kinetics at GPCRs is required to suc...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
North Holland Publishing
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406023/ https://www.ncbi.nlm.nih.gov/pubmed/30738950 http://dx.doi.org/10.1016/j.mce.2019.01.018 |