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Binding kinetics of ligands acting at GPCRs

The influence of drug-receptor binding kinetics has often been overlooked during the development of new therapeutics that target G protein-coupled receptors (GPCRs). Over the last decade there has been a growing understanding that an in-depth knowledge of binding kinetics at GPCRs is required to suc...

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Detalles Bibliográficos
Autores principales: Sykes, David A., Stoddart, Leigh A., Kilpatrick, Laura E., Hill, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: North Holland Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406023/
https://www.ncbi.nlm.nih.gov/pubmed/30738950
http://dx.doi.org/10.1016/j.mce.2019.01.018

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