Successful debulking of plurihormonal pituitary macroadenoma with long‐acting pasireotide and dopamine agonist combination therapy

Long‐acting pasireotide and bromocriptine provided biochemical control of growth hormone and prolactin in a patient with plurihormonal pituitary macroadenoma, allowing near‐complete tumor excision while restoring pituitary function and avoiding adjunctive radiotherapy. Pasireotide initiation resulte...

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Autores principales: Jerkins, Terri W., Jerkins, Randy K., Franklin, Robbi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406151/
https://www.ncbi.nlm.nih.gov/pubmed/30899469
http://dx.doi.org/10.1002/ccr3.1961
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author Jerkins, Terri W.
Jerkins, Randy K.
Franklin, Robbi
author_facet Jerkins, Terri W.
Jerkins, Randy K.
Franklin, Robbi
author_sort Jerkins, Terri W.
collection PubMed
description Long‐acting pasireotide and bromocriptine provided biochemical control of growth hormone and prolactin in a patient with plurihormonal pituitary macroadenoma, allowing near‐complete tumor excision while restoring pituitary function and avoiding adjunctive radiotherapy. Pasireotide initiation resulted in hyperglycemia, which stabilized after a few months and resolved upon pasireotide discontinuation (ACCESS; NCT01995734).
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spelling pubmed-64061512019-03-21 Successful debulking of plurihormonal pituitary macroadenoma with long‐acting pasireotide and dopamine agonist combination therapy Jerkins, Terri W. Jerkins, Randy K. Franklin, Robbi Clin Case Rep Case Reports Long‐acting pasireotide and bromocriptine provided biochemical control of growth hormone and prolactin in a patient with plurihormonal pituitary macroadenoma, allowing near‐complete tumor excision while restoring pituitary function and avoiding adjunctive radiotherapy. Pasireotide initiation resulted in hyperglycemia, which stabilized after a few months and resolved upon pasireotide discontinuation (ACCESS; NCT01995734). John Wiley and Sons Inc. 2019-01-28 /pmc/articles/PMC6406151/ /pubmed/30899469 http://dx.doi.org/10.1002/ccr3.1961 Text en © 2019 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Jerkins, Terri W.
Jerkins, Randy K.
Franklin, Robbi
Successful debulking of plurihormonal pituitary macroadenoma with long‐acting pasireotide and dopamine agonist combination therapy
title Successful debulking of plurihormonal pituitary macroadenoma with long‐acting pasireotide and dopamine agonist combination therapy
title_full Successful debulking of plurihormonal pituitary macroadenoma with long‐acting pasireotide and dopamine agonist combination therapy
title_fullStr Successful debulking of plurihormonal pituitary macroadenoma with long‐acting pasireotide and dopamine agonist combination therapy
title_full_unstemmed Successful debulking of plurihormonal pituitary macroadenoma with long‐acting pasireotide and dopamine agonist combination therapy
title_short Successful debulking of plurihormonal pituitary macroadenoma with long‐acting pasireotide and dopamine agonist combination therapy
title_sort successful debulking of plurihormonal pituitary macroadenoma with long‐acting pasireotide and dopamine agonist combination therapy
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406151/
https://www.ncbi.nlm.nih.gov/pubmed/30899469
http://dx.doi.org/10.1002/ccr3.1961
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