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Computed tomography scan imaging in diagnosing acute uncomplicated pancreatitis: Usefulness vs cost

BACKGROUND: Literature has suggested that imaging is over-utilized in the diagnosis of pancreatitis. If the diagnosis of acute pancreatitis (AP) is established with abdominal pain and increased serum amylase or lipase activity without systemic signs of severe disease, computed tomography (CT) imagin...

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Autores principales: Kothari, Shana, Kalinowski, Michael, Kobeszko, Matthew, Almouradi, Tarek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406186/
https://www.ncbi.nlm.nih.gov/pubmed/30862996
http://dx.doi.org/10.3748/wjg.v25.i9.1080
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author Kothari, Shana
Kalinowski, Michael
Kobeszko, Matthew
Almouradi, Tarek
author_facet Kothari, Shana
Kalinowski, Michael
Kobeszko, Matthew
Almouradi, Tarek
author_sort Kothari, Shana
collection PubMed
description BACKGROUND: Literature has suggested that imaging is over-utilized in the diagnosis of pancreatitis. If the diagnosis of acute pancreatitis (AP) is established with abdominal pain and increased serum amylase or lipase activity without systemic signs of severe disease, computed tomography (CT) imaging may not be necessary. We hypothesize that among patients with uncomplicated acute pancreatitis (AUP), there is a significant number of unwarranted CT imaging studies. This imposes increased expenditure and cost in our healthcare system and does not improve hospital stay or management of AUP. AIM: To assess the overutilization and associated cost of CT imaging among patients meeting diagnostic criteria for AUP. METHODS: In this Institutional Review Board-approved retrospective, single-center study, we identified all adult patients admitted with AP from January 1, 2012 through October 1, 2017. Patients were identified via International Classification of Diseases (ICD-9) code for AP (577.0) and ICD-10 codes for different etiological AP (K85.9 unspecified, K85.0 idiopathic, K85.1 biliary, K85.2 alcohol-induced, K85.3 drug-induced, and K85.8 other). Diagnosis was confirmed by chart review using established non-imaging diagnostic criteria (presence of typical abdominal pain and elevated lipase or amylase greater than 3 times upper limit of normal). Ranson criteria and BISAP scores on presentation were calculated and patients that met scores less than or equal to 2 for both were included to suggest AUP. The utilization and cost of imaging in these patients were recorded. RESULTS: Between January 2012 and October 2017, 1305 patients presented to the emergency department with AP, and 405 patients (31%) met our inclusion criteria for AUP (201 males, 204 females; mean age 49 years, range 18-98). Of those, 210 patients (51.85%) underwent CT imaging. One patient (0.47%) had evidence of pancreatic necrosis, one patient had cyst formation (0.47%), and the remaining 208 patients (99.05%) had either normal CT scan imaging or findings consistent with mild AP without necrosis. The average cost of CT scan imaging was $4510 with a total cost of $947056. Median length of hospitalization stay was 3 d among both groups. Combining Ranson’s Criteria and BISAP score identified AUP in our patient population with an accuracy of 99.5%. CONCLUSION: CT imaging is unnecessary when AUP is diagnosed clinically and biochemically. Reducing overuse of diagnostic CT scans will decrease healthcare expenditure and radiation exposure to patients.
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spelling pubmed-64061862019-03-12 Computed tomography scan imaging in diagnosing acute uncomplicated pancreatitis: Usefulness vs cost Kothari, Shana Kalinowski, Michael Kobeszko, Matthew Almouradi, Tarek World J Gastroenterol Retrospective Study BACKGROUND: Literature has suggested that imaging is over-utilized in the diagnosis of pancreatitis. If the diagnosis of acute pancreatitis (AP) is established with abdominal pain and increased serum amylase or lipase activity without systemic signs of severe disease, computed tomography (CT) imaging may not be necessary. We hypothesize that among patients with uncomplicated acute pancreatitis (AUP), there is a significant number of unwarranted CT imaging studies. This imposes increased expenditure and cost in our healthcare system and does not improve hospital stay or management of AUP. AIM: To assess the overutilization and associated cost of CT imaging among patients meeting diagnostic criteria for AUP. METHODS: In this Institutional Review Board-approved retrospective, single-center study, we identified all adult patients admitted with AP from January 1, 2012 through October 1, 2017. Patients were identified via International Classification of Diseases (ICD-9) code for AP (577.0) and ICD-10 codes for different etiological AP (K85.9 unspecified, K85.0 idiopathic, K85.1 biliary, K85.2 alcohol-induced, K85.3 drug-induced, and K85.8 other). Diagnosis was confirmed by chart review using established non-imaging diagnostic criteria (presence of typical abdominal pain and elevated lipase or amylase greater than 3 times upper limit of normal). Ranson criteria and BISAP scores on presentation were calculated and patients that met scores less than or equal to 2 for both were included to suggest AUP. The utilization and cost of imaging in these patients were recorded. RESULTS: Between January 2012 and October 2017, 1305 patients presented to the emergency department with AP, and 405 patients (31%) met our inclusion criteria for AUP (201 males, 204 females; mean age 49 years, range 18-98). Of those, 210 patients (51.85%) underwent CT imaging. One patient (0.47%) had evidence of pancreatic necrosis, one patient had cyst formation (0.47%), and the remaining 208 patients (99.05%) had either normal CT scan imaging or findings consistent with mild AP without necrosis. The average cost of CT scan imaging was $4510 with a total cost of $947056. Median length of hospitalization stay was 3 d among both groups. Combining Ranson’s Criteria and BISAP score identified AUP in our patient population with an accuracy of 99.5%. CONCLUSION: CT imaging is unnecessary when AUP is diagnosed clinically and biochemically. Reducing overuse of diagnostic CT scans will decrease healthcare expenditure and radiation exposure to patients. Baishideng Publishing Group Inc 2019-03-07 2019-03-07 /pmc/articles/PMC6406186/ /pubmed/30862996 http://dx.doi.org/10.3748/wjg.v25.i9.1080 Text en ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
spellingShingle Retrospective Study
Kothari, Shana
Kalinowski, Michael
Kobeszko, Matthew
Almouradi, Tarek
Computed tomography scan imaging in diagnosing acute uncomplicated pancreatitis: Usefulness vs cost
title Computed tomography scan imaging in diagnosing acute uncomplicated pancreatitis: Usefulness vs cost
title_full Computed tomography scan imaging in diagnosing acute uncomplicated pancreatitis: Usefulness vs cost
title_fullStr Computed tomography scan imaging in diagnosing acute uncomplicated pancreatitis: Usefulness vs cost
title_full_unstemmed Computed tomography scan imaging in diagnosing acute uncomplicated pancreatitis: Usefulness vs cost
title_short Computed tomography scan imaging in diagnosing acute uncomplicated pancreatitis: Usefulness vs cost
title_sort computed tomography scan imaging in diagnosing acute uncomplicated pancreatitis: usefulness vs cost
topic Retrospective Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406186/
https://www.ncbi.nlm.nih.gov/pubmed/30862996
http://dx.doi.org/10.3748/wjg.v25.i9.1080
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