Cargando…
Identification of Novel HLA Class II-Restricted Neoantigens Derived from Driver Mutations
Neoantigens derived from tumor-specific genetic mutations might be suitable targets for cancer immunotherapy because of their high immunogenicity. In the current study, we evaluated the immunogenicity of 10 driver mutations that are frequently expressed in various cancers using peripheral blood mono...
Autores principales: | Iiizumi, Susumu, Ohtake, Junya, Murakami, Naoko, Kouro, Taku, Kawahara, Mamoru, Isoda, Fumiko, Hamana, Hiroshi, Kishi, Hiroyuki, Nakamura, Norihiro, Sasada, Tetsuro |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406322/ https://www.ncbi.nlm.nih.gov/pubmed/30813491 http://dx.doi.org/10.3390/cancers11020266 |
Ejemplares similares
-
Exhaustion of CAR T cells: potential causes and solutions
por: Kouro, Taku, et al.
Publicado: (2022) -
Structural engineering of chimeric antigen receptors targeting HLA-restricted neoantigens
por: Hwang, Michael S., et al.
Publicado: (2021) -
Identification of HLA class I-restricted immunogenic neoantigens in triple negative breast cancer
por: Aparicio, Belén, et al.
Publicado: (2022) -
Immune Responses to Epidermal Growth Factor Receptor (EGFR) and Their Application for Cancer Treatment
por: Sasada, Tetsuro, et al.
Publicado: (2016) -
HLA class-I and class-II restricted neoantigen loads predict overall survival in breast cancer
por: Ren, Yingxue, et al.
Publicado: (2020)