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Revisiting Telomere Shortening in Cancer
Telomeres, the protective structures of chromosome ends are gradually shortened by each cell division, eventually leading to senescence or apoptosis. Cancer cells maintain the telomere length for unlimited growth by telomerase reactivation or a recombination-based mechanism. Recent genome-wide analy...
Autores principales: | Okamoto, Keiji, Seimiya, Hiroyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406355/ https://www.ncbi.nlm.nih.gov/pubmed/30709063 http://dx.doi.org/10.3390/cells8020107 |
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