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Revisiting Telomere Shortening in Cancer

Telomeres, the protective structures of chromosome ends are gradually shortened by each cell division, eventually leading to senescence or apoptosis. Cancer cells maintain the telomere length for unlimited growth by telomerase reactivation or a recombination-based mechanism. Recent genome-wide analy...

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Detalles Bibliográficos
Autores principales: Okamoto, Keiji, Seimiya, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406355/
https://www.ncbi.nlm.nih.gov/pubmed/30709063
http://dx.doi.org/10.3390/cells8020107

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