Structural and Dynamical Order of a Disordered Protein: Molecular Insights into Conformational Switching of PAGE4 at the Systems Level

Folded proteins show a high degree of structural order and undergo (fairly constrained) collective motions related to their functions. On the other hand, intrinsically disordered proteins (IDPs), while lacking a well-defined three-dimensional structure, do exhibit some structural and dynamical order...

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Detalles Bibliográficos
Autores principales: Lin, Xingcheng, Kulkarni, Prakash, Bocci, Federico, Schafer, Nicholas P., Roy, Susmita, Tsai, Min-Yeh, He, Yanan, Chen, Yihong, Rajagopalan, Krithika, Mooney, Steven M., Zeng, Yu, Weninger, Keith, Grishaev, Alex, Onuchic, José N., Levine, Herbert, Wolynes, Peter G., Salgia, Ravi, Rangarajan, Govindan, Uversky, Vladimir, Orban, John, Jolly, Mohit Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406393/
https://www.ncbi.nlm.nih.gov/pubmed/30813315
http://dx.doi.org/10.3390/biom9020077

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