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Risk Score to Predict Dental Caries in Adult Patients for Use in the Clinical Setting
Background: There is a need for risk prediction tools in caries research. This investigation aimed to estimate and evaluate a risk score for prediction of dental caries. Materials and Methods: This case-cohort study included a random sample of 177 cases (with dental caries) and 220 controls (randoml...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406458/ https://www.ncbi.nlm.nih.gov/pubmed/30736404 http://dx.doi.org/10.3390/jcm8020203 |
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author | de Araújo Nobre, Miguel Sezinando, Ana Fernandes, Inês Maló, Paulo |
author_facet | de Araújo Nobre, Miguel Sezinando, Ana Fernandes, Inês Maló, Paulo |
author_sort | de Araújo Nobre, Miguel |
collection | PubMed |
description | Background: There is a need for risk prediction tools in caries research. This investigation aimed to estimate and evaluate a risk score for prediction of dental caries. Materials and Methods: This case-cohort study included a random sample of 177 cases (with dental caries) and 220 controls (randomly sampled from the study population at baseline), followed for 3 years. The risk ratio (RR) for each potential predictor was estimated using a logistic regression model. The level of significance was 5%. Results: The risk model for dental caries included the predictors: “presence of bacterial plaque/calculus” (RR = 4.1), “restorations with more than 5 years” (RR = 2.3), “>8 teeth restored” (RR = 2.0), “history/active periodontitis” (RR = 1.7) and “presence of systemic condition” (RR = 1.4). The risk model discrimination (95% confidence interval) was 0.78 (0.73; 0.82) (p < 0.001, C-statistic). Patients were distributed into three risk groups based on the pre-analysis risk (54%): low risk (<half the pre-analysis risk; caries incidence = 6.8%), moderate risk (half-to-less than the pre-analysis risk; caries incidence = 20.4%) and high risk (≥the pre-analysis risk; caries incidence = 27%). Conclusions: The present study estimated a simple risk score for prediction of dental caries retrieved from a risk algorithm with good discrimination. |
format | Online Article Text |
id | pubmed-6406458 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-64064582019-03-22 Risk Score to Predict Dental Caries in Adult Patients for Use in the Clinical Setting de Araújo Nobre, Miguel Sezinando, Ana Fernandes, Inês Maló, Paulo J Clin Med Article Background: There is a need for risk prediction tools in caries research. This investigation aimed to estimate and evaluate a risk score for prediction of dental caries. Materials and Methods: This case-cohort study included a random sample of 177 cases (with dental caries) and 220 controls (randomly sampled from the study population at baseline), followed for 3 years. The risk ratio (RR) for each potential predictor was estimated using a logistic regression model. The level of significance was 5%. Results: The risk model for dental caries included the predictors: “presence of bacterial plaque/calculus” (RR = 4.1), “restorations with more than 5 years” (RR = 2.3), “>8 teeth restored” (RR = 2.0), “history/active periodontitis” (RR = 1.7) and “presence of systemic condition” (RR = 1.4). The risk model discrimination (95% confidence interval) was 0.78 (0.73; 0.82) (p < 0.001, C-statistic). Patients were distributed into three risk groups based on the pre-analysis risk (54%): low risk (<half the pre-analysis risk; caries incidence = 6.8%), moderate risk (half-to-less than the pre-analysis risk; caries incidence = 20.4%) and high risk (≥the pre-analysis risk; caries incidence = 27%). Conclusions: The present study estimated a simple risk score for prediction of dental caries retrieved from a risk algorithm with good discrimination. MDPI 2019-02-07 /pmc/articles/PMC6406458/ /pubmed/30736404 http://dx.doi.org/10.3390/jcm8020203 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article de Araújo Nobre, Miguel Sezinando, Ana Fernandes, Inês Maló, Paulo Risk Score to Predict Dental Caries in Adult Patients for Use in the Clinical Setting |
title | Risk Score to Predict Dental Caries in Adult Patients for Use in the Clinical Setting |
title_full | Risk Score to Predict Dental Caries in Adult Patients for Use in the Clinical Setting |
title_fullStr | Risk Score to Predict Dental Caries in Adult Patients for Use in the Clinical Setting |
title_full_unstemmed | Risk Score to Predict Dental Caries in Adult Patients for Use in the Clinical Setting |
title_short | Risk Score to Predict Dental Caries in Adult Patients for Use in the Clinical Setting |
title_sort | risk score to predict dental caries in adult patients for use in the clinical setting |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406458/ https://www.ncbi.nlm.nih.gov/pubmed/30736404 http://dx.doi.org/10.3390/jcm8020203 |
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