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Risk Score to Predict Dental Caries in Adult Patients for Use in the Clinical Setting

Background: There is a need for risk prediction tools in caries research. This investigation aimed to estimate and evaluate a risk score for prediction of dental caries. Materials and Methods: This case-cohort study included a random sample of 177 cases (with dental caries) and 220 controls (randoml...

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Autores principales: de Araújo Nobre, Miguel, Sezinando, Ana, Fernandes, Inês, Maló, Paulo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406458/
https://www.ncbi.nlm.nih.gov/pubmed/30736404
http://dx.doi.org/10.3390/jcm8020203
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author de Araújo Nobre, Miguel
Sezinando, Ana
Fernandes, Inês
Maló, Paulo
author_facet de Araújo Nobre, Miguel
Sezinando, Ana
Fernandes, Inês
Maló, Paulo
author_sort de Araújo Nobre, Miguel
collection PubMed
description Background: There is a need for risk prediction tools in caries research. This investigation aimed to estimate and evaluate a risk score for prediction of dental caries. Materials and Methods: This case-cohort study included a random sample of 177 cases (with dental caries) and 220 controls (randomly sampled from the study population at baseline), followed for 3 years. The risk ratio (RR) for each potential predictor was estimated using a logistic regression model. The level of significance was 5%. Results: The risk model for dental caries included the predictors: “presence of bacterial plaque/calculus” (RR = 4.1), “restorations with more than 5 years” (RR = 2.3), “>8 teeth restored” (RR = 2.0), “history/active periodontitis” (RR = 1.7) and “presence of systemic condition” (RR = 1.4). The risk model discrimination (95% confidence interval) was 0.78 (0.73; 0.82) (p < 0.001, C-statistic). Patients were distributed into three risk groups based on the pre-analysis risk (54%): low risk (<half the pre-analysis risk; caries incidence = 6.8%), moderate risk (half-to-less than the pre-analysis risk; caries incidence = 20.4%) and high risk (≥the pre-analysis risk; caries incidence = 27%). Conclusions: The present study estimated a simple risk score for prediction of dental caries retrieved from a risk algorithm with good discrimination.
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spelling pubmed-64064582019-03-22 Risk Score to Predict Dental Caries in Adult Patients for Use in the Clinical Setting de Araújo Nobre, Miguel Sezinando, Ana Fernandes, Inês Maló, Paulo J Clin Med Article Background: There is a need for risk prediction tools in caries research. This investigation aimed to estimate and evaluate a risk score for prediction of dental caries. Materials and Methods: This case-cohort study included a random sample of 177 cases (with dental caries) and 220 controls (randomly sampled from the study population at baseline), followed for 3 years. The risk ratio (RR) for each potential predictor was estimated using a logistic regression model. The level of significance was 5%. Results: The risk model for dental caries included the predictors: “presence of bacterial plaque/calculus” (RR = 4.1), “restorations with more than 5 years” (RR = 2.3), “>8 teeth restored” (RR = 2.0), “history/active periodontitis” (RR = 1.7) and “presence of systemic condition” (RR = 1.4). The risk model discrimination (95% confidence interval) was 0.78 (0.73; 0.82) (p < 0.001, C-statistic). Patients were distributed into three risk groups based on the pre-analysis risk (54%): low risk (<half the pre-analysis risk; caries incidence = 6.8%), moderate risk (half-to-less than the pre-analysis risk; caries incidence = 20.4%) and high risk (≥the pre-analysis risk; caries incidence = 27%). Conclusions: The present study estimated a simple risk score for prediction of dental caries retrieved from a risk algorithm with good discrimination. MDPI 2019-02-07 /pmc/articles/PMC6406458/ /pubmed/30736404 http://dx.doi.org/10.3390/jcm8020203 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
de Araújo Nobre, Miguel
Sezinando, Ana
Fernandes, Inês
Maló, Paulo
Risk Score to Predict Dental Caries in Adult Patients for Use in the Clinical Setting
title Risk Score to Predict Dental Caries in Adult Patients for Use in the Clinical Setting
title_full Risk Score to Predict Dental Caries in Adult Patients for Use in the Clinical Setting
title_fullStr Risk Score to Predict Dental Caries in Adult Patients for Use in the Clinical Setting
title_full_unstemmed Risk Score to Predict Dental Caries in Adult Patients for Use in the Clinical Setting
title_short Risk Score to Predict Dental Caries in Adult Patients for Use in the Clinical Setting
title_sort risk score to predict dental caries in adult patients for use in the clinical setting
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406458/
https://www.ncbi.nlm.nih.gov/pubmed/30736404
http://dx.doi.org/10.3390/jcm8020203
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